Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARB | P10826 | 8/20 | 0.52 |
| ▸ | RARA | P10276 | 7/20 | 0.52 |
| ▸ | RARG | P13631 | 5/20 | 0.52 |
| ▸ | RXRA | P19793 | 6/20 | 0.42 |
| ▸ | HNF4A | P41235 | 2/20 | 0.42 |
| ▸ | PDK2 | Q15119 | 2/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.40 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.40 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.40 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.40 |
| ▸ | RXRG | P48443 | 3/20 | 0.40 |
| ▸ | RXRB | P28702 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9119758 | 0.93 | RARB (0.53) | RARBRARARARGRXRAHNF4A | |
| SCHEMBL9050623 | 0.91 | RARB (0.52) | RARBRARARARGRXRAHNF4A | |
| SCHEMBL9117300 | 0.88 | RARB (0.54) | RARBRARARARGRXRAHNF4A | |
| SCHEMBL9051778 | 0.87 | RARB (0.53) | RARBRARARARGRXRAHNF4A | |
| SCHEMBL9051144 | 0.86 | RARB (0.53) | RARBRARARARGRXRAHNF4A | |
| SCHEMBL9049309 | 0.85 | RARB (0.52) | RARBRARARARGRXRAHNF4A | |
| SCHEMBL9120469 | 0.85 | RARB (0.52) | RARBRARARARGRXRAHNF4A | |
| SCHEMBL9048881 | 0.84 | RARB (0.66) | RARBRARARARGRXRARXRG | |
| SCHEMBL9051247 | 0.84 | RARA (0.53) | RARBRARARARGRXRAHNF4A | |
| SCHEMBL9050117 | 0.84 | RARB (0.51) | RARBRARARARGRXRAHNF4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1995033745-A9 | NOVEL COMPOUNDS USEFUL IN MODULATING GENE EXPRESSION OF RETINOID RESPONSIVE GENES AND/OR HAVING ANTI-AP-1 ACTIVITY | — | 1996-01-18 | — | — | WO | disclosed |
| WO-1995033745-A2 | NOVEL COMPOUNDS USEFUL IN MODULATING GENE EXPRESSION OF RETINOID RESPONSIVE GENES AND/OR HAVING ANTI-AP-1 ACTIVITY | SRI INTERNATIONAL (US) | 1995-12-14 | — | — | WO | disclosed |