Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.69 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.69 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.69 |
| ▸ | MAPT | P10636 | 2/20 | 0.69 |
| ▸ | AHR | P35869 | 1/20 | 0.69 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.69 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.69 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.65 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.65 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.65 |
| ▸ | HPGD | P15428 | 1/20 | 0.65 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.63 |
| ▸ | TSHR | P16473 | 1/20 | 0.63 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.63 |
| ▸ | HTR2A | P28223 | 6/20 | 0.61 |
| ▸ | HTR1A | P08908 | 4/20 | 0.61 |
| ▸ | HTR6 | P50406 | 3/20 | 0.61 |
| ▸ | HTR2C | P28335 | 3/20 | 0.60 |
| ▸ | HTR1D | P28221 | 2/20 | 0.60 |
| ▸ | HTR1B | P28222 | 2/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29413080 | 1.00 | MEN1 (0.69) | MEN1KMT2ACYP3A4MAPTAHR | |
| Dimethylamine SCHEMBL27471470 | 0.92 | MEN1 (0.66) | MEN1KMT2ACYP3A4MAPTAHR | |
| Acetic Acid SCHEMBL8374511 | 0.91 | KMT2A (0.63) | MEN1KMT2ACYP3A4MAPTAHR | |
| Phosphoric Acid SCHEMBL22235321 | 0.91 | MEN1 (0.58) | MEN1KMT2ACYP3A4MAPTAHR | |
| SCHEMBL30688540 | 0.86 | MEN1 (0.57) | MEN1KMT2ACYP3A4MAPTAHR | |
| SCHEMBL10481528 | 0.86 | MEN1 (0.57) | MEN1KMT2ACYP3A4MAPTAHR | |
| Ethoxycarbonyl Group SCHEMBL27785547 | 0.85 | PKM (0.55) | MEN1KMT2ACYP3A4MAPTAHR | |
| SCHEMBL29414676 | 0.83 | HTR2A (0.72) | MEN1KMT2ACYP3A4MAPTAHR | |
| SCHEMBL91128 | 0.83 | HTR2A (0.72) | MEN1KMT2ACYP3A4MAPTAHR | |
| SCHEMBL6524121 | 0.83 | MEN1 (0.69) | MEN1KMT2ACYP3A4MAPTAHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 2803 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116396291-A | Application of 1-amide and 1-hydrazide substituted beta-carboline derivative as agricultural bactericide | 南京农业大学 | 2023-07-07 | — | — | CN | claimed |
| CN-116284021-A | Compounds having therapeutic effect on bladder cancer | 湖南大学 | 2023-06-23 | — | — | CN | claimed |
| CN-112574092-B | Green novel method for preparing 2-diaryl methyl substituted indole compound | 湖南理工学院 | 2022-08-30 | — | — | CN | claimed |
| US-11021454-B2 | Type of aryl benzofuran amidated derivative and medical use thereof | CHINA PHARMACEUTICAL UNIVERSITY (CN) | 2021-06-01 | — | — | US | claimed |
| CN-112574092-A | Green novel method for preparing 2-diaryl methyl substituted indole compound | 湖南理工学院 | 2021-03-30 | — | — | CN | claimed |
| CN-111747981-A | Transition metal compound and preparation method and application thereof | 万华化学集团股份有限公司 | 2020-10-09 | — | — | CN | claimed |
| CN-110156729-A | A kind of phenylpiperazine class UBE2F micromolecular inhibitor and its synthetic method | 浙江大学 | 2019-08-23 | — | — | CN | claimed |
| US-20190040029-A1 | A type of aryl benzofuran amidated derivative and medical use thereof | CHINA PHARMACEUTICAL UNIVERSITY (CN) | 2019-02-07 | — | — | US | claimed |
| CN-107586284-A | A kind of purposes of 2 arylbenzofuran analog derivative in gout medicine is prepared | 中国药科大学 | 2018-01-16 | — | — | CN | claimed |
| WO-2017160361-A1 | POLYISOCYANURATE CATALYSTS FOR METAL PANELS AND SPRAY FOAMS | HUNTSMAN PETROCHEMICAL LLC (US) | 2017-09-21 | — | — | WO | claimed |
| EP-1214330-A1 | BENZIMIDAZOLE DERIVATIVES AND COMBINATORIAL LIBRARIES THEREOF | LION Bioscience AG (DE) | 2002-06-19 | — | — | EP | claimed |
| WO-2001021634-A1 | BENZIMIDAZOLE DERIVATIVES AND COMBINATORIAL LIBRARIES THEREOF | LION BIOSCIENCE AG (DE) | 2001-03-29 | — | — | WO | claimed |
| EP-0773024-A2 | Use of N-substituted nicotinamide compounds for the treatment of acute and chronic inflammatory diseases | PFIZER INC. (US) | 1997-05-14 | — | — | EP | claimed |
| US-5393760-A | Cardiovascular disorders, antitumor agents | HOFFMANN-LA ROCHE INC. (US) | 1995-02-28 | — | — | US | claimed |
| EP-0468231-B1 | Guanidins | HOFFMANN LA ROCHE (CH) | 1994-09-21 | — | — | EP | claimed |
| US-5260307-A | Inhibit thrombin-induced platlet aggregation and clotting of fibrogen in plasma | HOFMANN-LA ROCHE INC. (US) | 1993-11-09 | — | — | US | claimed |
| EP-0357316-B1 | ANTIDEPRESSANT N-SUBSTITUTED NICOTINAMIDE COMPOUNDS | PFIZER INC. (US) | 1993-04-14 | — | — | EP | claimed |
| EP-0422178-A1 | PYRIMIDINE DERIVATIVES. | ICI PLC (GB) | 1991-04-17 | — | — | EP | claimed |
| EP-0357316-A1 | Antidepressant N-substituted nicotinamide compounds | PFIZER INC. (US) | 1990-03-07 | — | — | EP | claimed |
| US-4861891-A | Antidepressant N-substituted nicotinamide compounds | PFIZER INC. (US) | 1989-08-29 | — | — | US | claimed |