Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4B | Q07343 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 3/20 | 0.48 |
| ▸ | RAB9A | P51151 | 3/20 | 0.48 |
| ▸ | CES2 | O00748 | 2/20 | 0.47 |
| ▸ | CES1 | P23141 | 2/20 | 0.47 |
| ▸ | CA1 | P00915 | 1/20 | 0.47 |
| ▸ | CA2 | P00918 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 2/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | PPARG | P37231 | 1/20 | 0.43 |
| ▸ | PPARA | Q07869 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | GSK3B | P49841 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Satigrel SCHEMBL379555 | 0.98 | PDE4B (0.54) | PDE4BALDH1A1CYP1A2HPGDCYP2C19 | |
| SCHEMBL9549165 | 0.93 | PDE4B (0.49) | PDE4BALDH1A1CYP1A2HPGDCYP2C19 | |
| SCHEMBL9549159 | 0.93 | PDE4B (0.49) | PDE4BALDH1A1CYP1A2HPGDCYP2C19 | |
| SCHEMBL9549180 | 0.93 | PDE4B (0.49) | PDE4BALDH1A1CYP1A2HPGDCYP2C19 | |
| SCHEMBL9549204 | 0.91 | PDE4B (0.61) | PDE4BALDH1A1CYP1A2HPGDCYP2C19 | |
| SCHEMBL9549325 | 0.90 | ALDH1A1 (0.49) | PDE4BALDH1A1CYP1A2HPGDCYP2C19 | |
| SCHEMBL9549320 | 0.90 | ALDH1A1 (0.49) | PDE4BALDH1A1CYP1A2HPGDCYP2C19 | |
| SCHEMBL9549067 | 0.86 | CA1 (0.49) | PDE4BALDH1A1CYP1A2HPGDCYP2C19 | |
| SCHEMBL9549213 | 0.84 | PDE4B (0.53) | PDE4BALDH1A1CYP1A2HPGDCYP2C19 | |
| SCHEMBL9549205 | 0.84 | PDE4B (0.53) | PDE4BALDH1A1CYP1A2HPGDCYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-8268886-A | — | — | None | — | — | JP | disclosed |
| JP-H08268886-A | SUPPRESSING AGENT FOR VASCULARIZATION | EISAI CO LTD | 1996-10-15 | — | — | JP | disclosed |