Propylene Glycol

Propylene Glycol

SCHEMBL9050495

CC(O)CO.CC1(OC2(C)CCCCC2)CCCCC1

nearest known ligand 0.43

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

SLC5A2

The experimentally established mechanism targets of Propylene Glycol. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 1/20 0.43
CYP19A1 P11511 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Propylene Glycol SCHEMBL27801474 0.98 TDP1 (0.46) TDP1CYP19A1
Propylene Glycol SCHEMBL9050440 0.78 TDP1 (0.43) TDP1
SCHEMBL10640995 0.78 CYP19A1 (0.31) CYP19A1
SCHEMBL11591113 0.78 CYP19A1 (0.31) CYP19A1
SCHEMBL197983 0.78 CYP19A1 (0.31) CYP19A1
Propylene Glycol SCHEMBL9136026 0.77 CYP2C19 (0.37) TDP1
Propylene Glycol SCHEMBL27341660 0.77 TDP1 (0.42) TDP1
SCHEMBL11682784 0.75
SCHEMBL196711 0.75
Propylene Glycol SCHEMBL28029489 0.75 TDP1 (0.50) TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1043882-C Propylene glycol cyclohexyl ether derivatives, method of producing same and uses thereof ASAHI CHEMICAL IND (JP) 1999-06-30 CN claimed
CN-1100712-A Propylene glycol cyclohexyl ether derivatives, method of producing same and uses thereof ASAHI CHEMICAL IND (JP) 1995-03-29 CN claimed
JP-7090298-A None JP disclosed
JP-8012807-A None JP disclosed
CN-108129937-B Normal-temperature solvent type road marking paint and preparation method thereof 天途路业集团有限公司 2020-08-21 CN disclosed
CN-101646718-B Curable resin composition, protective film, and method for forming protective film JSR CORP JP 2013-04-03 CN disclosed
CN-101646718-A The formation method of curable resin composition, protective membrane and protective membrane JSR CORP JP 2010-02-10 CN disclosed
CN-1043882-C Propylene glycol cyclohexyl ether derivatives, method of producing same and uses thereof ASAHI CHEMICAL IND (JP) 1999-06-30 CN disclosed
JP-H0812807-A POLYMER EMULSION COMPOSITION AND COMPOSITION FOR PAPER COATING ASAHI CHEM IND CO LTD 1996-01-16 JP disclosed
JP-H0790298-A CLEANING AGENT ASAHI CHEM IND CO LTD 1995-04-04 JP disclosed
CN-1100712-A Propylene glycol cyclohexyl ether derivatives, method of producing same and uses thereof ASAHI CHEMICAL IND (JP) 1995-03-29 CN disclosed
JP-H00790298-A 0001-01-01 JP disclosed