Propylene Glycol

Propylene Glycol

SCHEMBL9050440

CC(O)CO.OC1(OC2(O)CCCCC2)CCCCC1

nearest known ligand 0.43

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

SLC5A2

The experimentally established mechanism targets of Propylene Glycol. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 1/20 0.43
TSHR P16473 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Propylene Glycol SCHEMBL9136224 0.85 TDP1 (0.42) TDP1TSHR
Propylene Glycol SCHEMBL28029489 0.79 TDP1 (0.50) TDP1TSHR
Propylene Glycol SCHEMBL9050495 0.78 TDP1 (0.43) TDP1
SCHEMBL4802913 0.78 ALDH1A1 (0.36)
Propylene Glycol SCHEMBL27341660 0.77 TDP1 (0.42) TDP1
Propylene Glycol SCHEMBL27801474 0.76 TDP1 (0.46) TDP1
SCHEMBL27443560 0.75 ALDH1A1 (0.32)
SCHEMBL9050444 0.74 TSHR (0.38) TSHR
Propylene Glycol SCHEMBL27343974 0.74 TDP1 (0.39) TDP1
Propylene Glycol SCHEMBL8672848 0.70 TDP1 (0.67) TDP1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-8012841-A None JP disclosed
JP-H0812841-A ACRYLIC RESIN EMULSION COMPOSITION ASAHI CHEM IND CO LTD 1996-01-16 JP disclosed