Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 2/20 | 0.55 |
| ▸ | CES2 | O00748 | 4/20 | 0.54 |
| ▸ | CES1 | P23141 | 4/20 | 0.54 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.50 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.50 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.47 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.46 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.44 |
| ▸ | FAAH | O00519 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8680600 | 0.81 | CA1 (0.59) | CA1CES2CES1FFAR4FFAR1 | |
| SCHEMBL7628357 | 0.81 | CA1 (0.59) | CA1CES2CES1FFAR4FFAR1 | |
| SCHEMBL11115354 | 0.76 | CA1 (0.57) | CA1CES2FFAR4FFAR1ACE2 | |
| SCHEMBL9073848 | 0.76 | CA1 (0.57) | CA1CES2FFAR4FFAR1ACE2 | |
| SCHEMBL10904396 | 0.76 | CA1 (0.57) | CA1CES2FFAR4FFAR1ACE2 | |
| SCHEMBL10904395 | 0.76 | CA1 (0.57) | CA1CES2FFAR4FFAR1ACE2 | |
| SCHEMBL8798464 | 0.76 | CA1 (0.61) | CA1FFAR4FFAR1GPR84ACE2 | |
| SCHEMBL8799892 | 0.76 | CA1 (0.61) | CA1FFAR4FFAR1GPR84ACE2 | |
| SCHEMBL8800896 | 0.76 | CA1 (0.61) | CA1FFAR4FFAR1GPR84ACE2 | |
| SCHEMBL15022175 | 0.74 | CA1 (0.95) | CA1FFAR4FFAR1GPR84ACE2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1996040694-A1 | CARBONOTHIOATE PHOSPHOLIPID ANALOGS AS SUBSTRATE OF PHOSPHOLIPASES AND LIPASES | LA JOLLA PHARMACEUTICAL COMPANY (US) | 1996-12-19 | — | — | WO | disclosed |