Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 2/20 | 0.59 |
| ▸ | CES2 | O00748 | 4/20 | 0.58 |
| ▸ | CES1 | P23141 | 4/20 | 0.58 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.53 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.53 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.50 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.48 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.47 |
| ▸ | FAAH | O00519 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | CA2 | P00918 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7628357 | 1.00 | CA1 (0.59) | CA1CES2CES1FFAR4FFAR1 | |
| SCHEMBL28241003 | 0.83 | CES2 (0.58) | CA1CES2CES1 | |
| SCHEMBL10835912 | 0.82 | CES2 (0.56) | CES2CES1FFAR4FFAR1GPR84 | |
| SCHEMBL28294448 | 0.81 | CES2 (0.65) | CES2CES1FFAR4FFAR1GPR84 | |
| SCHEMBL9050682 | 0.81 | CA1 (0.55) | CA1CES2CES1FFAR4FFAR1 | |
| SCHEMBL16329078 | 0.81 | CA1 (0.46) | CA1CES2CES1FFAR4GPR84 | |
| SCHEMBL17391206 | 0.81 | CA1 (0.55) | CA1FFAR4FFAR1GPR84ACE2 | |
| SCHEMBL10904396 | 0.79 | CA1 (0.57) | CA1CES2FFAR4FFAR1ACE2 | |
| SCHEMBL8114261 | 0.79 | CA1 (0.57) | CA1FFAR4FFAR1GPR84ACE2 | |
| SCHEMBL11115354 | 0.79 | CA1 (0.57) | CA1CES2FFAR4FFAR1ACE2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5744649-A | CATALYSTS | UNION CARBIDE CHEMICALS & PLASTICS TECHNOLOGY CORPORATION (US) | 1998-04-28 | — | — | US | disclosed |
| US-5744650-A | USING METAL-ORGANOPOLYPHOSPHITE LIGAND COMPLEX CATALYST AND CONTROLLING CARBON MONOXIDE PARTIAL PRESSURE AND TEMPERATURE | UNION CARBIDE CHEMICALS & PLASTICS TECHNOLOGY CORPORATION (US) | 1998-04-28 | — | — | US | disclosed |