SCHEMBL9050752

SCHEMBL9050752

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nearest known ligand 0.32

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.32
SMN1; SMN2 Q16637 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11496825 1.00 TSHR (0.32) TSHRSMN1; SMN2
SCHEMBL9051445 0.79 MEN1 (0.31) TSHRSMN1; SMN2
SCHEMBL4474067 0.79 MEN1 (0.31) TSHRSMN1; SMN2
SCHEMBL8432379 0.76 TRPV1 (0.39)
SCHEMBL1634844 0.75
SCHEMBL4650572 0.75 TSHR (0.34) TSHRSMN1; SMN2
SCHEMBL1290407 0.75
SCHEMBL3685107 0.75
SCHEMBL1425004 0.74
SCHEMBL3509339 0.74

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-1996038465-A1 ALKYL 2β-MORPHOLINO-ANDROSTANE DERIVATIVES AKZO NOBEL N.V. (NL) 1996-12-05 WO disclosed