Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DAO | P14920 | 1/20 | 0.54 |
| ▸ | KAT8 | Q9H7Z6 | 2/20 | 0.49 |
| ▸ | PPARA | Q07869 | 2/20 | 0.49 |
| ▸ | RARB | P10826 | 7/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | RARA | P10276 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | MTOR | P42345 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | PPARG | P37231 | 1/20 | 0.46 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.45 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.45 |
| ▸ | RARG | P13631 | 1/20 | 0.44 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9148963 | 1.00 | DAO (0.54) | DAOKAT8PPARARARBALDH1A1 | |
| SCHEMBL8390700 | 1.00 | DAO (0.54) | DAOKAT8PPARARARBALDH1A1 | |
| SCHEMBL5858576 | 0.98 | DAO (0.55) | DAOKAT8PPARARARBALDH1A1 | |
| SCHEMBL6899153 | 0.86 | DAO (0.60) | DAOHCAR2 | |
| SCHEMBL9151583 | 0.83 | BAZ2B (0.51) | PPARAALDH1A1MEN1KMT2APPARG | |
| SCHEMBL9154517 | 0.83 | BAZ2B (0.51) | PPARAALDH1A1MEN1KMT2APPARG | |
| SCHEMBL9147935 | 0.83 | BAZ2B (0.51) | PPARAALDH1A1MEN1KMT2APPARG | |
| SCHEMBL9196174 | 0.83 | KDM4E (0.48) | KAT8PPARAALDH1A1GPR84PTGS2 | |
| SCHEMBL9516348 | 0.81 | MEN1 (0.44) | DAOKAT8PPARAALDH1A1MEN1 | |
| SCHEMBL9151658 | 0.81 | PPARA (0.44) | PPARAPPARGGPR84PTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-8012573-A | — | — | None | — | — | JP | disclosed |
| JP-H0812573-A | FREE FATTY ACID REDUCING AGENT | MITSUBISHI CHEM CORP | 1996-01-16 | — | — | JP | disclosed |
| US-RE35096-E | Antilipemic, anticholesterol, arteriosclerosis | MITSUBISHI CHEMICAL CORPORATION (JP) | 1995-11-21 | — | — | US | disclosed |
| US-5082856-A | Hyperlipemia, arteriosclerosis | MITSUBISHI KASEI CORPORATION (JP) | 1992-01-21 | — | — | US | disclosed |
| EP-0347902-A2 | Pyrrolecarboxylic acid derivatives | Mitsubishi Chemical Corporation (JP) | 1989-12-27 | — | — | EP | disclosed |