Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | GPR84 | Q9NQS5 | 2/20 | 0.41 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.41 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.40 |
| ▸ | THRA | P10827 | 3/20 | 0.39 |
| ▸ | THRB | P10828 | 3/20 | 0.39 |
| ▸ | KAT8 | Q9H7Z6 | 2/20 | 0.39 |
| ▸ | PPARA | Q07869 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | SPHK2 | Q9NRA0 | 1/20 | 0.39 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.39 |
| ▸ | PLA2G1B | P04054 | 2/20 | 0.38 |
| ▸ | ATG4B | Q9Y4P1 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23952162 | 0.87 | GAA (0.53) | KDM4EALDH1A1GAA | |
| SCHEMBL8390700 | 0.83 | DAO (0.54) | ALDH1A1GPR84PTGS2KAT8PPARA | |
| SCHEMBL9148963 | 0.83 | DAO (0.54) | ALDH1A1GPR84PTGS2KAT8PPARA | |
| SCHEMBL9050786 | 0.83 | DAO (0.54) | ALDH1A1GPR84PTGS2KAT8PPARA | |
| SCHEMBL9147935 | 0.82 | BAZ2B (0.51) | ALDH1A1GAAGPR84PTGS2PPARA | |
| SCHEMBL9154517 | 0.82 | BAZ2B (0.51) | ALDH1A1GAAGPR84PTGS2PPARA | |
| SCHEMBL9151583 | 0.82 | BAZ2B (0.51) | ALDH1A1GAAGPR84PTGS2PPARA | |
| SCHEMBL9194572 | 0.81 | KDM4E (0.42) | KDM4EALDH1A1GAACYP3A4 | |
| SCHEMBL5858576 | 0.81 | DAO (0.55) | ALDH1A1GPR84PTGS2KAT8PPARA | |
| SCHEMBL23952165 | 0.80 | GAA (0.55) | KDM4EALDH1A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0434070-B1 | Pyrrolealdehyde derivative | MITSUBISHI CHEM CORP (JP) | 1995-08-09 | — | — | EP | disclosed |
| US-5153217-A | Antiiipemic, anticholesterol agents | MITSUBISHI KASEI CORPORATION (JP) | 1992-10-06 | — | — | US | disclosed |
| EP-0434070-A2 | Pyrrolealdehyde derivative | Mitsubishi Chemical Corporation (JP) | 1991-06-26 | — | — | EP | disclosed |