Known targets — ChEMBL curated mechanism
ACHECHKACHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNB1CHRNDCHRNECHRNGHRH2OPRM1
The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM3 known ✓ | P20309 | 20/20 | 0.60 |
| ▸ | CHRM2 known ✓ | P08172 | 9/20 | 0.60 |
| ▸ | CHRM1 known ✓ | P11229 | 8/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5007267 | 0.84 | CHRM3 (0.55) | CHRM3CHRM2CHRM1 | |
| SCHEMBL9050182 | 0.81 | CHRM3 (0.68) | CHRM3CHRM2CHRM1 | |
| Iodide SCHEMBL9048201 | 0.81 | CHRM3 (0.83) | CHRM3CHRM2CHRM1 | |
| SCHEMBL5011140 | 0.79 | CHRM3 (0.50) | CHRM3CHRM2CHRM1 | |
| SCHEMBL5011305 | 0.78 | CHRM3 (0.48) | CHRM3CHRM2CHRM1 | |
| SCHEMBL13399275 | 0.77 | CHRM3 (0.51) | CHRM3CHRM2CHRM1 | |
| Bromide SCHEMBL1190936 | 0.77 | CHRM3 (0.58) | CHRM3CHRM2CHRM1 | |
| Bromide SCHEMBL1190949 | 0.77 | CHRM3 (0.53) | CHRM3CHRM2CHRM1 | |
| Bromide SCHEMBL1190950 | 0.77 | CHRM3 (0.53) | CHRM3CHRM2CHRM1 | |
| Bromide SCHEMBL1190934 | 0.77 | CHRM3 (0.58) | CHRM3CHRM2CHRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0747355-A1 | NOVEL CARBAMATE DERIVATIVE AND MEDICINAL COMPOSITION CONTAINING THE SAME | YAMANOUCHI PHARMACEUTICAL CO. LTD. (JP) | 1996-12-11 | — | — | EP | disclosed |