Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 12/20 | 0.46 |
| ▸ | MAP4K4 | O95819 | 3/20 | 0.33 |
| ▸ | SCD | O00767 | 2/20 | 0.33 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.32 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.32 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.32 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.32 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.32 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.32 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.32 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL905117 | 0.79 | GPR119 (0.60) | GPR119 | |
| SCHEMBL905095 | 0.77 | GPR119 (0.55) | GPR119 | |
| SCHEMBL905139 | 0.72 | GPR119 (0.67) | GPR119 | |
| SCHEMBL10034542 | 0.72 | GPR119 (0.76) | GPR119 | |
| SCHEMBL905150 | 0.72 | GPR119 (0.76) | GPR119 | |
| SCHEMBL905159 | 0.72 | GPR119 (0.76) | GPR119 | |
| SCHEMBL10034543 | 0.71 | GPR119 (0.77) | GPR119 | |
| SCHEMBL10034540 | 0.71 | GPR119 (0.65) | GPR119 | |
| SCHEMBL905154 | 0.71 | GPR119 (0.64) | GPR119 | |
| SCHEMBL905089 | 0.69 | GPR119 (0.62) | GPR119 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012043505-A1 | NOVEL PIPERIDINE DERIVATIVE AND PHARMACEUTICAL CONTAINING SAME | 興和株式会社 (JP) | 2012-04-05 | — | — | WO | disclosed |