SCHEMBL9051002

SCHEMBL9051002

NC(=O)C(CN=C(c1ccccc1)c1ccccc1)C1CCc2c(cccc2OCC(=O)O)C1

nearest known ligand 0.59

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
PTGIR P43119 20/20 0.59
PTGDR Q13258 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9048146 0.85 PTGIR (0.60) PTGIRPTGDR
SCHEMBL9048122 0.83 PTGIR (0.58) PTGIRPTGDR
SCHEMBL9427242 0.82 PTGIR (0.59) PTGIRPTGDR
SCHEMBL9427367 0.81 PTGIR (0.56) PTGIRPTGDR
SCHEMBL9050354 0.80 PTGIR (0.57) PTGIRPTGDR
SCHEMBL9050333 0.77 PTGIR (0.56) PTGIRPTGDR
SCHEMBL8858441 0.73 PTGIR (0.58) PTGIRPTGDR
SCHEMBL9047535 0.73 PTGIR (0.62) PTGIRPTGDR
SCHEMBL7772422 0.73 PTGIR (0.60) PTGIR
SCHEMBL9048596 0.72 PTGIR (0.43) PTGIRPTGDR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0542203-B1 Fused benzeneoxyacetic acid derivatives as PGl2 receptor agonists ONO PHARMACEUTICAL CO (JP) 1996-07-03 EP claimed
US-5344836-A Fused benzeneoxyacetic acid derivatives ONO PHARMACEUTICAL CO., LTD. (JP) 1994-09-06 US claimed