Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGIR | P43119 | 17/20 | 0.43 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | ACHE | P22303 | 1/20 | 0.35 |
| ▸ | PTGDR | Q13258 | 2/20 | 0.34 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.34 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.34 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9048146 | 0.86 | PTGIR (0.60) | PTGIRPTGDR | |
| SCHEMBL9050999 | 0.83 | PTGIR (0.48) | PTGIRPTGDR | |
| SCHEMBL9046342 | 0.82 | PTGIR (0.38) | PTGIRACHE | |
| SCHEMBL9567947 | 0.80 | TRPM8 (0.39) | CA1CA2MTNR1AMTNR1B | |
| SCHEMBL9427236 | 0.79 | PTGIR (0.43) | PTGIRCA1CA2ACHEMTNR1A | |
| SCHEMBL9427127 | 0.78 | PTGIR (0.43) | PTGIRACHE | |
| SCHEMBL9427442 | 0.78 | PTGIR (0.41) | PTGIRCA1CA2ACHEMTNR1A | |
| SCHEMBL9048119 | 0.78 | PTGIR (0.42) | PTGIRCA1CA2ACHEMTNR1A | |
| SCHEMBL9427048 | 0.74 | PTGIR (0.52) | PTGIR | |
| SCHEMBL9048009 | 0.73 | TBXAS1 (0.44) | PTGIRPTGDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0542203-B1 | Fused benzeneoxyacetic acid derivatives as PGl2 receptor agonists | ONO PHARMACEUTICAL CO (JP) | 1996-07-03 | — | — | EP | claimed |