SCHEMBL9051602

SCHEMBL9051602

CCOC(=O)Nc1ccccc1N1CCCCC1

nearest known ligand 0.63

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NPSR1 Q6W5P4 5/20 0.63
L3MBTL1 Q9Y468 5/20 0.63
MAPT P10636 4/20 0.63
GAA P10253 3/20 0.60
CYP1A2 P05177 2/20 0.60
CYP2D6 P10635 2/20 0.60
CYP2C9 P11712 2/20 0.60
CYP2C19 P33261 1/20 0.60
ATM Q13315 2/20 0.60
MEN1 O00255 2/20 0.60
KMT2A Q03164 2/20 0.60
POLB P06746 3/20 0.59
MAPK1 P28482 2/20 0.59
LMNA P02545 2/20 0.59
USP2 O75604 1/20 0.59
ALOX15 P16050 1/20 0.59
TSHR P16473 2/20 0.59
KCNQ2 O43526 3/20 0.57
ALDH1A1 P00352 1/20 0.56
KCNQ3 O43525 1/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28032896 0.86 LMNA (0.65) NPSR1L3MBTL1CYP1A2CYP2C9CYP2C19
SCHEMBL13763656 0.85 NPSR1 (0.65) NPSR1L3MBTL1MAPTGAAATM
SCHEMBL12732483 0.85 CYP1A2 (0.60) NPSR1L3MBTL1MAPTGAACYP1A2
SCHEMBL7896507 0.81 MAPT (0.64) NPSR1L3MBTL1MAPTGAACYP1A2
SCHEMBL13757457 0.81 GAA (0.61) NPSR1L3MBTL1MAPTGAACYP1A2
SCHEMBL19700180 0.80 CYP1A2 (0.47) NPSR1L3MBTL1MAPTGAACYP1A2
Hydrochloric Acid SCHEMBL7896677 0.80 MAPT (0.62) NPSR1L3MBTL1MAPTGAACYP1A2
SCHEMBL1643994 0.79 NPSR1 (0.68) NPSR1L3MBTL1MAPTGAAATM
SCHEMBL12736832 0.79 MAPT (0.71) NPSR1MAPTGAACYP1A2CYP2D6
SCHEMBL4318899 0.79 KCNQ2 (0.68) NPSR1L3MBTL1MAPTGAACYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0747355-A1 NOVEL CARBAMATE DERIVATIVE AND MEDICINAL COMPOSITION CONTAINING THE SAME YAMANOUCHI PHARMACEUTICAL CO. LTD. (JP) 1996-12-11 EP disclosed