Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GCGR | P47871 | 2/20 | 0.44 |
| ▸ | CNR2 | P34972 | 1/20 | 0.43 |
| ▸ | KAT8 | Q9H7Z6 | 4/20 | 0.42 |
| ▸ | PPARA | Q07869 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.42 |
| ▸ | HTR2B | P41595 | 1/20 | 0.42 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.42 |
| ▸ | DHFR | P00374 | 1/20 | 0.39 |
| ▸ | DPP4 | P27487 | 1/20 | 0.39 |
| ▸ | BID | P55957 | 3/20 | 0.39 |
| ▸ | MCL1 | Q07820 | 3/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL981445 | 0.80 | GCGR (0.55) | GCGRCNR2KAT8PPARAMEN1 | |
| SCHEMBL982000 | 0.80 | GCGR (0.54) | GCGRCNR2DHFR | |
| SCHEMBL9050810 | 0.79 | GCGR (0.42) | GCGRCNR2MEN1NR1I2LMNA | |
| SCHEMBL984920 | 0.79 | GCGR (0.53) | GCGRCNR2KAT8PPARAMEN1 | |
| SCHEMBL984780 | 0.79 | GCGR (0.53) | GCGRCNR2KAT8PPARAMEN1 | |
| SCHEMBL983338 | 0.79 | GCGR (0.53) | GCGRCNR2KAT8PPARAMEN1 | |
| SCHEMBL982876 | 0.79 | GCGR (0.53) | GCGRCNR2KAT8PPARAMEN1 | |
| SCHEMBL984798 | 0.79 | GCGR (0.53) | GCGRCNR2KAT8PPARAMEN1 | |
| SCHEMBL982595 | 0.79 | GCGR (0.53) | GCGRCNR2KAT8PPARAMEN1 | |
| SCHEMBL983918 | 0.79 | GCGR (0.52) | GCGRKAT8PPARAMEN1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0722439-A1 | HIV PROTEASE INHIBITORS | AGOURON PHARMACEUTICALS, INC. (US) | 1996-07-24 | — | — | EP | disclosed |