SCHEMBL9051869

SCHEMBL9051869

C=C(Br)c1ccccc1Cl

nearest known ligand 0.52

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
CES2 O00748 1/20 0.52
CES1 P23141 1/20 0.52
ALDH1A1 P00352 3/20 0.50
POLB P06746 2/20 0.46
LMNA P02545 1/20 0.43
TSHR P16473 1/20 0.43
CYP1A2 P05177 2/20 0.41
HPGD P15428 2/20 0.41
CYP2C19 P33261 1/20 0.41
ERCC5 P28715 1/20 0.39
FEN1 P39748 1/20 0.39
MGLL Q99685 1/20 0.37
RECQL P46063 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9493916 0.79 CES2 (0.56) CES2CES1ALDH1A1POLBLMNA
SCHEMBL675024 0.77 CES2 (0.54) CES2CES1ALDH1A1POLBLMNA
SCHEMBL29444187 0.77 CES2 (0.54) CES2CES1ALDH1A1POLBLMNA
SCHEMBL2270560 0.75 CES2 (0.52) CES2CES1ALDH1A1POLBLMNA
SCHEMBL2325272 0.75 CES2 (0.65) CES2CES1ALDH1A1POLBTSHR
SCHEMBL1028918 0.75 CES2 (0.52) CES2CES1ALDH1A1POLBLMNA
SCHEMBL8444340 0.75 CES2 (0.46) CES2CES1ALDH1A1POLBLMNA
SCHEMBL2349523 0.73 CES2 (0.50) CES2CES1ALDH1A1POLBLMNA
SCHEMBL28565913 0.73 CES2 (0.50) CES2CES1ALDH1A1POLBLMNA
SCHEMBL4416667 0.73 CES2 (0.62) CES2CES1ALDH1A1POLBLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-1996036634-A1 OXIRANYL-HYDROXYETHYL TRIAZOLES BAYER AKTIENGESELLSCHAFT (DE) 1996-11-21 WO disclosed
WO-1996036635-A1 OXIRANYL-TRIAZOLES BAYER AKTIENGESELLSCHAFT (DE) 1996-11-21 WO disclosed