Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.45 |
| ▸ | HTT | P42858 | 3/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | BACE1 | P56817 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | TAS2R14 | Q9NYV8 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | GLA | P06280 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | CNR2 | P34972 | 3/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | MMP2 | P08253 | 1/20 | 0.36 |
| ▸ | MMP9 | P14780 | 1/20 | 0.36 |
| ▸ | MMP8 | P22894 | 1/20 | 0.36 |
| ▸ | MMP13 | P45452 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3539599 | 0.88 | MAPT (0.43) | MAPTHTTALDH1A1MAPK1BACE1 | |
| SCHEMBL3512796 | 0.88 | MAPT (0.43) | MAPTHTTALDH1A1MAPK1BACE1 | |
| SCHEMBL9052588 | 0.85 | MAPT (0.42) | MAPTHTTALDH1A1MAPK1BACE1 | |
| SCHEMBL9052583 | 0.85 | MAPT (0.42) | MAPTHTTALDH1A1MAPK1BACE1 | |
| SCHEMBL2335489 | 0.82 | GLA (0.50) | MAPTHTTLMNAGLACNR2 | |
| SCHEMBL9052348 | 0.81 | GLA (0.40) | MAPTHTTALDH1A1MAPK1KDM4E | |
| SCHEMBL9593490 | 0.81 | GLA (0.46) | HTTALDH1A1LMNATAS2R14KMT2A | |
| SCHEMBL6443129 | 0.80 | GLA (0.49) | MAPTHTTLMNAGLACNR2 | |
| SCHEMBL15144440 | 0.77 | CA9 (0.50) | HTTALDH1A1LMNAKMT2AMEN1 | |
| SCHEMBL13096088 | 0.76 | CA1 (0.41) | ALDH1A1KMT2AMEN1CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1996038465-A1 | ALKYL 2β-MORPHOLINO-ANDROSTANE DERIVATIVES | AKZO NOBEL N.V. (NL) | 1996-12-05 | — | — | WO | disclosed |