Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 7/20 | 0.49 |
| ▸ | DRD4 | P21917 | 7/20 | 0.49 |
| ▸ | DRD3 | P35462 | 7/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | NPFFR1 | Q9GZQ6 | 1/20 | 0.42 |
| ▸ | NPFFR2 | Q9Y5X5 | 1/20 | 0.42 |
| ▸ | UBE2M | P61081 | 1/20 | 0.40 |
| ▸ | DCUN1D1 | Q96GG9 | 1/20 | 0.40 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.40 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.39 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.39 |
| ▸ | JAK1 | P23458 | 1/20 | 0.38 |
| ▸ | BCHE | P06276 | 1/20 | 0.38 |
| ▸ | ACHE | P22303 | 1/20 | 0.38 |
| ▸ | MC4R | P32245 | 1/20 | 0.38 |
| ▸ | KDM1A | O60341 | 1/20 | 0.38 |
| ▸ | MAOB | P27338 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9051882 | 1.00 | DRD2 (0.49) | DRD2DRD4DRD3KMT2AL3MBTL1 | |
| SCHEMBL3187519 | 0.91 | KMT2A (0.55) | DRD2DRD4DRD3KMT2AL3MBTL1 | |
| SCHEMBL7835003 | 0.91 | KMT2A (0.55) | DRD2DRD4DRD3KMT2AL3MBTL1 | |
| SCHEMBL1781856 | 0.91 | KMT2A (0.55) | DRD2DRD4DRD3KMT2AL3MBTL1 | |
| SCHEMBL19121559 | 0.91 | KMT2A (0.55) | DRD2DRD4DRD3KMT2AL3MBTL1 | |
| SCHEMBL7834998 | 0.91 | KMT2A (0.55) | DRD2DRD4DRD3KMT2AL3MBTL1 | |
| SCHEMBL3187533 | 0.91 | KMT2A (0.55) | DRD2DRD4DRD3KMT2AL3MBTL1 | |
| SCHEMBL6208015 | 0.87 | KMT2A (0.53) | DRD2DRD4DRD3KMT2AL3MBTL1 | |
| SCHEMBL6480037 | 0.87 | KMT2A (0.53) | DRD2DRD4DRD3KMT2AL3MBTL1 | |
| SCHEMBL1779389 | 0.83 | DRD2 (0.50) | DRD2DRD4DRD3KMT2AL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1996039407-A1 | QUINOLIZINONE TYPE COMPOUNDS | ABBOTT LABORATORIES (US) | 1996-12-12 | — | — | WO | disclosed |