Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | CHRNA1 | P02708 | 1/20 | 0.35 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.35 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.35 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.35 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15010366 | 0.75 | ALDH1A1 (0.38) | ALDH1A1MAPTL3MBTL1KDM4EGAA | |
| SCHEMBL12176791 | 0.75 | MAPT (0.40) | ALDH1A1MAPTL3MBTL1KDM4EGAA | |
| SCHEMBL3709897 | 0.72 | GAA (0.34) | ALDH1A1MAPTL3MBTL1KDM4EGAA | |
| SCHEMBL4634377 | 0.72 | GAA (0.41) | ALDH1A1L3MBTL1GAAMEN1KMT2A | |
| SCHEMBL12697280 | 0.71 | GAA (0.46) | ALDH1A1MAPTL3MBTL1KDM4EGAA | |
| SCHEMBL12723416 | 0.71 | BCHE (0.34) | ALDH1A1MAPTL3MBTL1KDM4EGAA | |
| Hydrochloric Acid SCHEMBL9281543 | 0.70 | GAA (0.44) | ALDH1A1MAPTL3MBTL1KDM4EGAA | |
| SCHEMBL2891830 | 0.69 | PSEN1 (0.35) | ALDH1A1L3MBTL1TDP1CHRNA1CHRNA3 | |
| SCHEMBL1799946 | 0.69 | PSEN1 (0.33) | ALDH1A1L3MBTL1TDP1CHRNA1CHRNB2 | |
| SCHEMBL245979 | 0.69 | ALDH1A1 (0.49) | ALDH1A1MAPTL3MBTL1KDM4EGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0556684-B1 | Process for the preparation of 2-chloro-5-alkylamino-methylpyridines | BAYER AG (DE) | 1996-05-22 | — | — | EP | claimed |
| US-5382671-A | Process for the preparation of 2-chloro-5-alkylaminomethyl-pyridines | BAYER AKTIENGESELLSCHAFT (DE) | 1995-01-17 | — | — | US | claimed |
| EP-0556684-A1 | Process for the preparation of 2-chloro-5-alkylamino-methylpyridines | BAYER AG (DE) | 1993-08-25 | — | — | EP | claimed |
| JP-6016635-A | — | — | None | — | — | JP | disclosed |
| CN-1042934-C | Process for preparing 2-chloro-5-alkylaminomethylpyridines | BAYER AG (DE) | 1999-04-14 | — | — | CN | disclosed |
| EP-0556684-B1 | Process for the preparation of 2-chloro-5-alkylamino-methylpyridines | BAYER AG (DE) | 1996-05-22 | — | — | EP | disclosed |
| US-5382671-A | Process for the preparation of 2-chloro-5-alkylaminomethyl-pyridines | BAYER AKTIENGESELLSCHAFT (DE) | 1995-01-17 | — | — | US | disclosed |
| US-5382671-A | Process for the preparation of 2-chloro-5-alkylaminomethyl-pyridines | BAYER AKTIENGESELLSCHAFT (DE) | 1995-01-17 | — | — | US | disclosed |
| JP-H0616635-A | PRODUCTION OF 2-CHLORO-5-ALKYLALOMINOMETHYL-PYRIDINES | BAYER AG | 1994-01-25 | — | — | JP | disclosed |
| EP-0556684-A1 | Process for the preparation of 2-chloro-5-alkylamino-methylpyridines | BAYER AG (DE) | 1993-08-25 | — | — | EP | disclosed |
| EP-0556684-A1 | Process for the preparation of 2-chloro-5-alkylamino-methylpyridines | BAYER AG (DE) | 1993-08-25 | — | — | EP | disclosed |