Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPY1R | P25929 | 10/20 | 0.47 |
| ▸ | HTR6 | P50406 | 1/20 | 0.47 |
| ▸ | MET | P08581 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.40 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | SLC40A1 | Q9NP59 | 1/20 | 0.39 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.38 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9050400 | 0.84 | NPY1R (0.65) | NPY1RHTR6METTSHRMEN1 | |
| SCHEMBL9050776 | 0.82 | NPY1R (0.47) | NPY1RHTR6METTSHRMEN1 | |
| SCHEMBL9050676 | 0.82 | NPY1R (0.65) | NPY1RMETTSHRMEN1TP53 | |
| SCHEMBL8986316 | 0.80 | NPY1R (0.62) | NPY1RMETTSHRMEN1KMT2A | |
| SCHEMBL8986379 | 0.80 | NPY1R (0.75) | NPY1RHTR6METTSHRMEN1 | |
| SCHEMBL8856476 | 0.80 | POLB (0.50) | TSHRMEN1CYP3A4MAPTKMT2A | |
| SCHEMBL9051632 | 0.79 | NPY1R (0.47) | NPY1RHTR6METTSHRMEN1 | |
| SCHEMBL9050312 | 0.78 | NPY1R (0.51) | NPY1RHTR6METTSHRNCOA1 | |
| SCHEMBL9052377 | 0.78 | NPY1R (0.54) | NPY1RMETTSHRMEN1TP53 | |
| SCHEMBL9050803 | 0.77 | NPY1R (0.52) | NPY1RMETTSHRMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1996037474-A1 | SULFONYLQUINOLINES AS NEUROPEPTIDE Y1 ANTAGONISTS | WARNER-LAMBERT COMPANY (US) | 1996-11-28 | — | — | WO | disclosed |