⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20641014 | 1.00 | — | — | |
| SCHEMBL6384594 | 1.00 | — | — | |
| Nitric Acid SCHEMBL8582389 | 0.95 | ALDH1A1 (0.40) | — | |
| SCHEMBL8399806 | 0.85 | — | — | |
| SCHEMBL2460940 | 0.85 | — | — | |
| SCHEMBL6380368 | 0.83 | ALDH1A1 (0.48) | — | |
| SCHEMBL11598670 | 0.81 | ALDH1A1 (0.37) | — | |
| SCHEMBL6929123 | 0.81 | ALDH1A1 (0.52) | — | |
| SCHEMBL8896820 | 0.81 | ALDH1A1 (0.52) | — | |
| SCHEMBL6261486 | 0.81 | ALDH1A1 (0.52) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11008358-B2 | Synthesis of desosamines | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2021-05-18 | — | — | US | disclosed |
| US-20200347087-A1 | SYNTHESIS OF DESOSAMINES | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2020-11-05 | — | — | US | disclosed |
| US-10544182-B2 | Synthesis of desosamines | Presidents and Fellow of Harvard College (US) | 2020-01-28 | — | — | US | disclosed |
| US-20180111956-A1 | SYNTHESIS OF DESOSAMINES | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2018-04-26 | — | — | US | disclosed |
| US-20180111956-A1 | SYNTHESIS OF DESOSAMINES | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2018-04-26 | — | — | US | disclosed |
| EP-3277701-A1 | SYNTHESIS OF DESOSAMINES | President and Fellows of Harvard College (US) | 2018-02-07 | — | — | EP | disclosed |
| WO-2016154533-A1 | SYNTHESIS OF DESOSAMINES | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2016-09-29 | — | — | WO | disclosed |
| WO-2016154533-A1 | SYNTHESIS OF DESOSAMINES | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2016-09-29 | — | — | WO | disclosed |
| WO-1996026933-A9 | NOVEL SELECTIVE INHIBITORS OF VIRAL OR BACTERIAL NEURAMINIDASES | — | 1996-11-28 | — | — | WO | disclosed |