Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | HLCS | P50747 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | S1PR2 | O95136 | 2/20 | 0.36 |
| ▸ | S1PR4 | O95977 | 2/20 | 0.36 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.36 |
| ▸ | S1PR3 | Q99500 | 2/20 | 0.36 |
| ▸ | S1PR5 | Q9H228 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | PRKCA | P17252 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8443031 | 1.00 | ALDH1A1 (0.45) | ALDH1A1L3MBTL1CYP1A2MEN1KMT2A | |
| SCHEMBL5518415 | 1.00 | ALDH1A1 (0.45) | ALDH1A1L3MBTL1CYP1A2MEN1KMT2A | |
| SCHEMBL13082563 | 0.98 | ALDH1A1 (0.47) | ALDH1A1L3MBTL1CYP1A2MEN1KMT2A | |
| SCHEMBL2780724 | 0.98 | ALDH1A1 (0.47) | ALDH1A1L3MBTL1CYP1A2MEN1KMT2A | |
| SCHEMBL6036825 | 0.98 | ALDH1A1 (0.47) | ALDH1A1L3MBTL1CYP1A2MEN1KMT2A | |
| SCHEMBL10337476 | 0.98 | ALDH1A1 (0.47) | ALDH1A1L3MBTL1CYP1A2MEN1KMT2A | |
| SCHEMBL474085 | 0.98 | ALDH1A1 (0.47) | ALDH1A1L3MBTL1CYP1A2MEN1KMT2A | |
| SCHEMBL1439579 | 0.86 | — | — | |
| SCHEMBL2365737 | 0.86 | — | — | |
| SCHEMBL1439581 | 0.86 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0362902-B1 | Process and intermediates for beta-lactam antibiotics | HARVARD COLLEGE (US) | 1996-01-17 | — | — | EP | disclosed |
| US-5091525-A | 7beta- 2'-(R)-2'-(p-hydroxyphenyl-2'-amino-acetamido!-3-chloro -3-(1-carbadethiacephem)-4-carboxylic acid | ELI LILLY AND COMPANY (US) | 1992-02-25 | — | — | US | disclosed |
| EP-0209352-B1 | PROCESS AND INTERMEDIATES FOR BETA-LACTAM ANTIBIOTICS | THE PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 1991-05-02 | — | — | EP | disclosed |
| US-4870169-A | Intermediates for beta-lactam antibiotics | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 1989-09-26 | — | — | US | disclosed |
| US-4775752-A | Process and intermediates for beta-lactam antibiotics | THE PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 1988-10-04 | — | — | US | disclosed |