Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 7/20 | 0.78 |
| ▸ | MEN1 | O00255 | 1/20 | 0.67 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.67 |
| ▸ | LMNA | P02545 | 1/20 | 0.67 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.67 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.64 |
| ▸ | SLC6A1 | P30531 | 1/20 | 0.61 |
| ▸ | SLC6A12 | P48065 | 1/20 | 0.61 |
| ▸ | SLC6A11 | P48066 | 1/20 | 0.61 |
| ▸ | CCR1 | P32246 | 1/20 | 0.59 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.58 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.58 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.58 |
| ▸ | HTR1A | P08908 | 1/20 | 0.58 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.58 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.58 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.58 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.58 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.58 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13211778 | 0.90 | DRD2 (0.66) | DRD2MEN1KMT2AADRA1ANR1I2 | |
| SCHEMBL9053094 | 0.89 | DRD2 (0.83) | DRD2MEN1KMT2AADRA1ANR1I2 | |
| SCHEMBL20652836 | 0.89 | DRD2 (0.74) | DRD2MEN1KMT2AADRA1ANR1I2 | |
| SCHEMBL20254450 | 0.89 | DRD2 (0.83) | DRD2MEN1KMT2AADRA1ANR1I2 | |
| SCHEMBL11793314 | 0.89 | DRD2 (0.83) | DRD2MEN1KMT2AADRA1ACYP1A2 | |
| SCHEMBL9051915 | 0.88 | DRD2 (0.73) | DRD2MEN1ALDH1A1LMNAKMT2A | |
| SCHEMBL3139717 | 0.88 | DRD2 (0.73) | DRD2MEN1ALDH1A1LMNAKMT2A | |
| SCHEMBL8986029 | 0.88 | DRD2 (1.00) | DRD2MEN1KMT2AADRA1ANR1I2 | |
| SCHEMBL9050723 | 0.87 | DRD2 (0.83) | DRD2MEN1KMT2AADRA1ANR1I2 | |
| SCHEMBL9052699 | 0.85 | DRD2 (0.80) | DRD2MEN1KMT2AADRA1ANR1I2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1996002250-A1 | HALOPERIDOL ANALOGS AND THE USE THEREOF | ACEA PHARMACEUTICALS INC. (US) | 1996-02-01 | — | — | WO | disclosed |