Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.62 |
| ▸ | MGAM | O43451 | 1/20 | 0.62 |
| ▸ | SI | P14410 | 1/20 | 0.62 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.62 |
| ▸ | TSHR | P16473 | 5/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.41 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.37 |
| ▸ | MMP8 | P22894 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6740870 | 0.96 | GAA (0.68) | GAAMGAMSIMGAM2TSHR | |
| SCHEMBL21925523 | 0.94 | GAA (0.65) | GAAMGAMSIMGAM2TSHR | |
| Butane SCHEMBL888582 | 0.94 | TSHR (0.50) | GAAMGAMSIMGAM2TSHR | |
| SCHEMBL243431 | 0.87 | TSHR (0.56) | GAAMGAMSIMGAM2TSHR | |
| SCHEMBL28235998 | 0.85 | TSHR (0.50) | GAAMGAMSIMGAM2TSHR | |
| Malonic Acid Diethyl Ester SCHEMBL456196 | 0.84 | GAA (0.88) | GAAMGAMSIMGAM2TSHR | |
| Butane SCHEMBL5526854 | 0.83 | TSHR (0.41) | GAAMGAMSIMGAM2TSHR | |
| SCHEMBL5068761 | 0.83 | MAPT (0.47) | GAAMGAMSIMGAM2TSHR | |
| SCHEMBL27827275 | 0.83 | CYP1A2 (0.48) | GAAMGAMSIMGAM2TSHR | |
| Malonic Acid Diethyl Ester SCHEMBL11237858 | 0.82 | GAA (0.75) | GAAMGAMSIMGAM2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1996001806-A1 | GLYCINAMIDE DERIVATIVES, PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME AND METHODS UTILIZING THE SAME | YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF JERUSALEM (IL) | 1996-01-25 | — | — | WO | disclosed |