Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.55 |
| ▸ | CETP | P11597 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | LAP3 | P28838 | 1/20 | 0.41 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | SRC | P12931 | 1/20 | 0.40 |
| ▸ | IDO1 | P14902 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 1/20 | 0.39 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.39 |
| ▸ | MTOR | P42345 | 1/20 | 0.39 |
| ▸ | ALPG | P10696 | 1/20 | 0.39 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | AGXT | P21549 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8361083 | 0.88 | TSHR (0.63) | TSHRCETPALDH1A1FOLH1NPC1 | |
| SCHEMBL6423059 | 0.80 | TSHR (0.59) | TSHRCETPALDH1A1LAP3FOLH1 | |
| SCHEMBL991032 | 0.80 | TSHR (0.59) | TSHRCETPALDH1A1LAP3FOLH1 | |
| SCHEMBL8619121 | 0.78 | TSHR (0.57) | TSHRCETPALDH1A1LAP3FOLH1 | |
| SCHEMBL28822078 | 0.78 | TSHR (0.57) | TSHRCETPALDH1A1LAP3FOLH1 | |
| SCHEMBL11145560 | 0.77 | TSHR (0.78) | TSHRCETPALDH1A1LAP3FOLH1 | |
| SCHEMBL2415748 | 0.77 | TSHR (0.55) | TSHRCETPALDH1A1LAP3FOLH1 | |
| SCHEMBL9570346 | 0.76 | TSHR (0.70) | TSHRCETPALDH1A1FOLH1NPC1 | |
| SCHEMBL9051512 | 0.76 | TSHR (0.53) | TSHRCETPALDH1A1LAP3FOLH1 | |
| SCHEMBL7290859 | 0.76 | TSHR (0.53) | TSHRCETPALDH1A1LAP3FOLH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1996000733-A1 | DIPHOSPHATE OR TRIPHOSPHATE NON-HYDROLYSABLE STABLE ANALOGUES AND METHODS FOR THEIR PREPARATION | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) | 1996-01-11 | — | — | WO | disclosed |