Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.52 |
| ▸ | CETP | P11597 | 3/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | SRC | P12931 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | ELANE | P08246 | 1/20 | 0.37 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.37 |
| ▸ | MTOR | P42345 | 1/20 | 0.37 |
| ▸ | ALPG | P10696 | 1/20 | 0.37 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.37 |
| ▸ | IDO1 | P14902 | 1/20 | 0.36 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5850148 | 0.91 | TSHR (0.61) | TSHRCETPHPGDALDH1A1SRC | |
| SCHEMBL10528706 | 0.84 | TSHR (0.53) | TSHRCETPHPGDALDH1A1SRC | |
| SCHEMBL4350991 | 0.82 | TSHR (0.52) | TSHRCETP | |
| SCHEMBL4154492 | 0.82 | TSHR (0.56) | TSHRCETPHPGDALDH1A1SRC | |
| SCHEMBL29182982 | 0.81 | TSHR (0.59) | TSHRCETPALDH1A1SRCNPC1 | |
| SCHEMBL13537853 | 0.81 | TSHR (0.50) | TSHRCETPHPGDNPC1RAB9A | |
| SCHEMBL7290859 | 0.80 | TSHR (0.53) | TSHRCETPHPGDALDH1A1SRC | |
| SCHEMBL218693 | 0.79 | TSHR (0.57) | TSHRCETPALDH1A1SRCNPC1 | |
| SCHEMBL10825547 | 0.79 | TSHR (0.52) | TSHRCETPHPGDSRC | |
| SCHEMBL12707989 | 0.78 | AKR1B1 (0.55) | TSHRCETPALDH1A1FOLH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1996000733-A1 | DIPHOSPHATE OR TRIPHOSPHATE NON-HYDROLYSABLE STABLE ANALOGUES AND METHODS FOR THEIR PREPARATION | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) | 1996-01-11 | — | — | WO | disclosed |