Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.61 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | CETP | P11597 | 3/20 | 0.46 |
| ▸ | IDO1 | P14902 | 1/20 | 0.43 |
| ▸ | SRC | P12931 | 1/20 | 0.42 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.42 |
| ▸ | MTOR | P42345 | 1/20 | 0.42 |
| ▸ | ALPG | P10696 | 1/20 | 0.42 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.42 |
| ▸ | AGXT | P21549 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | CA9 | Q16790 | 1/20 | 0.41 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9052908 | 0.91 | TSHR (0.52) | TSHRHPGDCETPIDO1SRC | |
| SCHEMBL4154492 | 0.91 | TSHR (0.56) | TSHRHPGDCETPSRCPDPK1 | |
| SCHEMBL4350991 | 0.91 | TSHR (0.52) | TSHRCETP | |
| SCHEMBL13537853 | 0.89 | TSHR (0.50) | TSHRHPGDCETPIDO1AGXT | |
| SCHEMBL7290859 | 0.88 | TSHR (0.53) | TSHRHPGDCETPSRCALDH1A1 | |
| SCHEMBL10528706 | 0.88 | TSHR (0.53) | TSHRHPGDCETPIDO1SRC | |
| SCHEMBL10825547 | 0.87 | TSHR (0.52) | TSHRHPGDCETPSRC | |
| SCHEMBL12707989 | 0.86 | AKR1B1 (0.55) | TSHRCETPALDH1A1CA2FOLH1 | |
| SCHEMBL7301510 | 0.85 | ALOX5 (0.47) | TSHRNPC1RAB9A | |
| SCHEMBL5327008 | 0.84 | TSHR (0.63) | TSHRCETPIDO1SRCPDPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250313471-A1 | MECHANOCHEMICAL REDUCTION OF PHOSPHATES AS A SUSTAINABLE ROUTE TO PHOSPHITE SALTS AND ORGANOPHOSPHITE COMPOUNDS | MASSACHUSETTS INST TECHNOLOGY (US) | 2025-10-09 | — | — | US | disclosed |
| US-7084194-B2 | Halogen-free resin composition | CHANG CHUN PLASTICS CO., LTD. (TW) | 2006-08-01 | — | — | US | disclosed |
| US-20040158023-A1 | Halogen-free resin composition | CHANG CHUN PLASTICS CO., LTD. (TW) | 2004-08-12 | — | — | US | disclosed |
| US-6200701-B1 | ELIMINATING THE FIRST CYCLE IRREVERSIBLE CAPACITY IN LITHIUM ION CELLS WHILE STILL MAINTAINING THE LOW TEMPERATURE CYCLING CAPABILITY BY ADDING A PHOSPHONATE, PREFERABLY DIALKYL, TO A NONAQUEOUS ORGANIC CARBON-ACTIVATING ELECTROLYTE | WILSON GREATBATCH LTD. | 2001-03-13 | — | — | US | disclosed |
| EP-0659188-A4 | METHODS FOR THE SYNTHESIS OF PHOSPHONATE ESTERS. | AFFYMAX TECH NV (AN) | 1995-11-22 | — | — | EP | disclosed |
| EP-0659188-A1 | METHODS FOR THE SYNTHESIS OF PHOSPHONATE ESTERS | AFFYMAX TECHNOLOGIES N.V. (AN) | 1995-06-28 | — | — | EP | disclosed |
| US-5420328-A | Esterification with alcohol and hydrolysis | AFFYMAX TECHNOLOGIES, N.V. (AN) | 1995-05-30 | — | — | US | disclosed |
| US-5359115-A | Reacting phosphonic monoester with dialkylazodicarboxylate, triphenylphosphine and secondary alcohol to form diester, hydrolyzing selective ester to form monoester, coupling an aminoacid to yield peptidylphosphonate | AFFYMAX TECHNOLOGIES, N.V. (US) | 1994-10-25 | — | — | US | disclosed |
| WO-1994006808-A1 | METHODS FOR THE SYNTHESIS OF PHOSPHONATE ESTERS | AFFYMAX TECHNOLOGIES N.V. (AN) | 1994-03-31 | — | — | WO | disclosed |
| US-4348333-A | β-Ketocarboxyl and phosphonate dihydro-chalcone sweeteners | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) | 1982-09-07 | — | — | US | disclosed |
| US-4233199-A | POLYPHENYLENE ETHER, STYRENE RESIN, PHOSPHORUS COMPOUND, ABSORBENT FILLER | ABOLINS VISVALDIS | 1980-11-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250313471-A1 | MECHANOCHEMICAL REDUCTION OF PHOSPHATES AS A SUSTAINABLE ROUTE TO PHOSPHITE SALTS AND ORGANOPHOSPHITE COMPOUNDS | PHOSPHO1, PSPH, PLCG1 | TSHR 4487/4885HPGD 4075/4885CETP 2145/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.