Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 4/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 11/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1463877 | 0.80 | EGFR (0.55) | EGFRKMT2AKDM4EHTTSMN1; SMN2 | |
| SCHEMBL8922268 | 0.76 | CYP3A4 (0.49) | EGFRKMT2AKDM4EHTTSMN1; SMN2 | |
| SCHEMBL1463590 | 0.75 | CYP3A4 (0.60) | EGFRKMT2AKDM4EHTTSMN1; SMN2 | |
| SCHEMBL1464587 | 0.75 | EGFR (0.67) | EGFRKMT2AKDM4EHTTSMN1; SMN2 | |
| SCHEMBL7770722 | 0.74 | CYP3A4 (0.42) | EGFRKMT2AKDM4EHTTSMN1; SMN2 | |
| SCHEMBL7770742 | 0.73 | CYP3A4 (0.46) | EGFRKMT2AKDM4EHTTSMN1; SMN2 | |
| SCHEMBL7770758 | 0.73 | CYP3A4 (0.48) | EGFRKMT2AKDM4EHTTSMN1; SMN2 | |
| SCHEMBL7768661 | 0.72 | CYP3A4 (0.46) | EGFRKMT2AKDM4EHTTSMN1; SMN2 | |
| SCHEMBL7768662 | 0.72 | CYP3A4 (0.46) | EGFRKMT2AKDM4EHTTSMN1; SMN2 | |
| SCHEMBL7769129 | 0.72 | CYP3A4 (0.44) | EGFRKMT2AKDM4EHTTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-8143586-A | — | — | None | — | — | JP | disclosed |
| JP-H08143586-A | PHOSPHONIC ACID DIESTER DERIVATIVE | OTSUKA PHARMACEUT FACTORY INC | 1996-06-04 | — | — | JP | disclosed |