Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 2/20 | 0.48 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.45 |
| ▸ | RAF1 | P04049 | 2/20 | 0.43 |
| ▸ | BRAF | P15056 | 2/20 | 0.43 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | ATR | Q13535 | 2/20 | 0.42 |
| ▸ | MAOA | P21397 | 1/20 | 0.41 |
| ▸ | MAOB | P27338 | 1/20 | 0.41 |
| ▸ | XDH | P47989 | 1/20 | 0.41 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.40 |
| ▸ | PRKDC | P78527 | 1/20 | 0.40 |
| ▸ | METAP2 | P50579 | 1/20 | 0.40 |
| ▸ | GRM5 | P41594 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6616427 | 1.00 | IDO1 (0.48) | IDO1ADORA2ARAF1BRAFPIK3CA | |
| SCHEMBL6621957 | 1.00 | IDO1 (0.48) | IDO1ADORA2ARAF1BRAFPIK3CA | |
| SCHEMBL6620411 | 0.86 | MAPK1 (0.46) | MAPK1ATRMAOAMAOBMETAP2 | |
| SCHEMBL6616740 | 0.86 | MAPK1 (0.46) | MAPK1ATRMAOAMAOBMETAP2 | |
| SCHEMBL6616738 | 0.82 | SMN1; SMN2 (0.58) | MAPK1CLK4 | |
| SCHEMBL6618680 | 0.81 | CDC7 (0.50) | IDO1PIK3CAMAPK1 | |
| SCHEMBL6619870 | 0.81 | BCHE (0.54) | IDO1MAPK1METAP2 | |
| SCHEMBL6617130 | 0.81 | BCHE (0.54) | IDO1MAPK1METAP2 | |
| SCHEMBL6617279 | 0.81 | BCHE (0.54) | IDO1RAF1BRAFPIK3CAMAPK1 | |
| SCHEMBL6616183 | 0.81 | EGFR (0.47) | IDO1MAPK1CLK4METAP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1996007658-A1 | PYRAZOLO[3,4-g]QUINOXALINE COMPOUNDS WHICH INHIBIT PDGF RECEPTOR PROTEIN TYROSINE KINASE | RHONE-POULENC RORER PHARMACEUTICALS INC. (US) | 1996-03-14 | — | — | WO | disclosed |