Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.35 |
| ▸ | MEN1 | O00255 | 3/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | GLA | P06280 | 1/20 | 0.35 |
| ▸ | NPY1R | P25929 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 2/20 | 0.35 |
| ▸ | GBA1 | P04062 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9029494 | 0.76 | SMN1; SMN2 (0.52) | MAPTMAPK1KMT2AMEN1TSHR | |
| SCHEMBL1063993 | 0.75 | MAPT (0.40) | MAPTMAPK1KMT2AMEN1TSHR | |
| SCHEMBL5485611 | 0.74 | CDC7 (0.30) | — | |
| SCHEMBL28256286 | 0.68 | ALDH1A1 (0.44) | KMT2AKDM4EGLAHSD17B10SMN1; SMN2 | |
| SCHEMBL17784880 | 0.68 | ALDH1A1 (0.44) | MAPTMAPK1KMT2AMEN1TSHR | |
| SCHEMBL7951223 | 0.68 | SLC29A1 (0.41) | MAPTMAPK1KMT2AMEN1TSHR | |
| SCHEMBL4316997 | 0.67 | TSHR (0.59) | MAPK1TSHRKDM4EHSD17B10SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL28169526 | 0.67 | ALDH1A1 (0.43) | MAPTKMT2AMEN1KDM4EGLA | |
| SCHEMBL1703128 | 0.66 | — | — | |
| SCHEMBL10456578 | 0.66 | ALDH1A1 (0.45) | MAPTMAPK1TSHRHSD17B10POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0345220-B1 | Polyamines partially substituted by bis-piperidyl-triazines | CIBA GEIGY AG (CH) | 1996-08-28 | — | — | EP | disclosed |
| EP-0345221-B1 | Polyamines partially substituted by piperidine-triazines | CIBA GEIGY AG (CH) | 1995-12-27 | — | — | EP | disclosed |
| US-4933451-A | LIGHT, HEAT AND OXIDATION STABILIZERS | CIBA-GEIGY CORPORATION (US) | 1990-06-12 | — | — | US | disclosed |
| US-4927930-A | LIGHT, HEAT AND OXIDATION STABILIZERS FOR POLYMERS | CIBA-GEIGY CORPORATION (US) | 1990-05-22 | — | — | US | disclosed |
| EP-0345221-A2 | Polyamines partially substituted by piperidine-triazines | CIBA-GEIGY AG (CH) | 1989-12-06 | — | — | EP | disclosed |
| EP-0345220-A2 | Polyamines partially substituted by bis-piperidyl-triazines | CIBA-GEIGY AG (CH) | 1989-12-06 | — | — | EP | disclosed |