Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 3/20 | 0.60 |
| ▸ | HRH1 | P35367 | 3/20 | 0.60 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.51 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.42 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.42 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.42 |
| ▸ | SCN1A | P35498 | 1/20 | 0.42 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.42 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19399095 | 0.87 | AOC3 (0.49) | HTR2AHRH1MTNR1AMTNR1BKDM4E | |
| SCHEMBL4942475 | 0.87 | AOC3 (0.49) | HTR2AHRH1MTNR1AMTNR1BKDM4E | |
| SCHEMBL3905618 | 0.84 | HRH1 (0.58) | HTR2AHRH1MTNR1AMTNR1BALDH1A1 | |
| SCHEMBL14217383 | 0.80 | HTR2A (0.53) | HTR2AHRH1MTNR1AMTNR1BALDH1A1 | |
| SCHEMBL18230943 | 0.79 | SLC6A9 (0.55) | SLC6A4 | |
| SCHEMBL7274896 | 0.77 | HTR2A (0.55) | HTR2AHRH1MTNR1AMTNR1BALDH1A1 | |
| SCHEMBL6893002 | 0.76 | KDM4E (0.49) | HTR2AHRH1ALDH1A1KDM4ELMNA | |
| SCHEMBL527127 | 0.76 | KDM4E (0.49) | HTR2AHRH1ALDH1A1KDM4ELMNA | |
| SCHEMBL10409938 | 0.76 | HTR2A (0.53) | HTR2AHRH1MTNR1AMTNR1BALDH1A1 | |
| SCHEMBL1802493 | 0.76 | HRH1 (1.00) | HTR2AHRH1ALDH1A1KDM4ESIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1996039137-A1 | INHIBITORS OF FARNESYL-PROTEIN TRANSFERASE | MERCK & CO., INC. (US) | 1996-12-12 | — | — | WO | disclosed |