Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 2/20 | 0.51 |
| ▸ | HTR2B | P41595 | 2/20 | 0.51 |
| ▸ | HTR2C | P28335 | 1/20 | 0.51 |
| ▸ | EPHX1 | P07099 | 7/20 | 0.51 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.50 |
| ▸ | IDO1 | P14902 | 2/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | ACP3 | P15309 | 1/20 | 0.46 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.45 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.45 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.45 |
| ▸ | DRD3 | P35462 | 1/20 | 0.45 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.45 |
| ▸ | MIF | P14174 | 1/20 | 0.45 |
| ▸ | DAO | P14920 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1145952 | 0.80 | HTR2A (0.56) | HTR2AHTR2BHTR2CEPHX1TAAR1 | |
| SCHEMBL23927275 | 0.80 | TAAR1 (0.58) | HTR2AHTR2BHTR2CEPHX1TAAR1 | |
| SCHEMBL23927281 | 0.80 | TAAR1 (0.58) | HTR2AHTR2BHTR2CEPHX1TAAR1 | |
| SCHEMBL7519147 | 0.77 | HTR2A (0.53) | HTR2AHTR2BHTR2CEPHX1TAAR1 | |
| SCHEMBL1145949 | 0.77 | TAAR1 (0.55) | HTR2AHTR2BHTR2CEPHX1TAAR1 | |
| SCHEMBL4268169 | 0.77 | TAAR1 (0.55) | HTR2AHTR2BHTR2CEPHX1TAAR1 | |
| SCHEMBL19592249 | 0.77 | TAAR1 (0.55) | HTR2AHTR2BHTR2CEPHX1TAAR1 | |
| SCHEMBL9053154 | 0.76 | HTR2A (0.51) | HTR2AHTR2BHTR2CEPHX1TAAR1 | |
| SCHEMBL46757 | 0.75 | HTR2A (0.63) | HTR2AHTR2BHTR2CEPHX1TAAR1 | |
| SCHEMBL25464586 | 0.75 | EPHX1 (0.50) | HTR2AHTR2BHTR2CEPHX1TAAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1996009046-A1 | 5α-REDUCTASE INHIBITORS | ELI LILLY AND COMPANY (US) | 1996-03-28 | — | — | WO | disclosed |