Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.48 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.48 |
| ▸ | CA12 | O43570 | 1/20 | 0.48 |
| ▸ | PARP1 | P09874 | 1/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.48 |
| ▸ | CA9 | Q16790 | 1/20 | 0.48 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.48 |
| ▸ | PRKCI | P41743 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | RAD52 | P43351 | 1/20 | 0.47 |
| ▸ | CTNNB1 | P35222 | 2/20 | 0.46 |
| ▸ | WNT3A | P56704 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.46 |
| ▸ | HPGD | P15428 | 3/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | QPCT | Q16769 | 2/20 | 0.46 |
| ▸ | QPCTL | Q9NXS2 | 2/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Benzimidazole SCHEMBL4441683 | 0.98 | SMN1; SMN2 (0.47) | SMN1; SMN2PDPK1CA12PARP1ALOX15 | |
| Benzimidazole SCHEMBL28217962 | 0.98 | SMN1; SMN2 (0.47) | SMN1; SMN2PDPK1CA12PARP1ALOX15 | |
| Benzimidazole SCHEMBL461969 | 0.97 | SMN1; SMN2 (0.50) | SMN1; SMN2PDPK1CA12PARP1ALOX15 | |
| Benzimidazole SCHEMBL29358377 | 0.97 | — | — | |
| Benzimidazole SCHEMBL29408372 | 0.97 | — | — | |
| Benzimidazole SCHEMBL6009 | 0.97 | — | — | |
| Benzimidazole SCHEMBL10931770 | 0.97 | SMN1; SMN2 (0.50) | SMN1; SMN2PDPK1CA12PARP1ALOX15 | |
| Benzimidazole SCHEMBL23673327 | 0.95 | SMN1; SMN2 (0.48) | SMN1; SMN2PDPK1CA12PARP1ALOX15 | |
| Benzimidazole SCHEMBL21046391 | 0.95 | — | — | |
| Benzimidazole SCHEMBL22551123 | 0.95 | SMN1; SMN2 (0.48) | SMN1; SMN2PDPK1CA12PARP1ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106632256-A | Synthesis method of proton pump inhibitors | 河南师范大学 | 2017-05-10 | — | — | CN | disclosed |
| CN-1636564-A | Composition and pharmaceutical preparation containing alkoxy-substituted benzimidazole compound and preparation method thereof | AAIPHARMA INC (US) | 2005-07-13 | — | — | CN | disclosed |
| CN-1107503-C | Optically pure compound as medicinal use | ASTRA CO LTD (SE) | 2003-05-07 | — | — | CN | disclosed |
| CN-1100776-C | Process for preparing magnesium salt of substituted sulphinyl heterocycle | ASTRA AB (SE) | 2003-02-05 | — | — | CN | disclosed |
| CN-1259346-A | Optically pure compound as medicinal use | ASTRA CO LTD (SE) | 2000-07-12 | — | — | CN | disclosed |
| CN-1216989-A | Process for preparing magnesium salt of substituted sulphinyl heterocycle | ASTRA AB (SE) | 1999-05-19 | — | — | CN | disclosed |
| CN-1134667-A | Multiple unit tablet containing proton pump inhibitor | ASTRA AB (SE) | 1996-10-30 | — | — | CN | disclosed |
| EP-0724434-A1 | MULTIPLE UNIT TABLETED DOSAGE FORM CONTAINING PROTON PUMP INHIBITOR | Astra Aktiebolag (SE) | 1996-08-07 | — | — | EP | disclosed |
| WO-1996001625-A1 | MULTIPLE UNIT TABLETED DOSAGE FORM CONTAINING PROTON PUMP INHIBITOR | ASTRA AKTIEBOLAG (SE) | 1996-01-25 | — | — | WO | disclosed |