Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR1 | P32246 | 8/20 | 0.77 |
| ▸ | DRD2 | P14416 | 5/20 | 0.70 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.70 |
| ▸ | DRD3 | P35462 | 2/20 | 0.70 |
| ▸ | LMNA | P02545 | 1/20 | 0.70 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.60 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.60 |
| ▸ | CCR3 | P51677 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9106963 | 0.87 | CCR1 (1.00) | CCR1 | |
| SCHEMBL11792972 | 0.83 | DRD2 (0.88) | CCR1DRD2SIGMAR1DRD3LMNA | |
| Hydroxyhaloperidol SCHEMBL4540106 | 0.82 | DRD2 (1.00) | CCR1DRD2SIGMAR1DRD3LMNA | |
| SCHEMBL11932477 | 0.79 | CCR1 (0.69) | CCR1DRD2SIGMAR1DRD3LMNA | |
| SCHEMBL9107609 | 0.78 | CCR1 (1.00) | CCR1 | |
| SCHEMBL904905 | 0.78 | DRD2 (0.83) | CCR1DRD2SIGMAR1DRD3LMNA | |
| SCHEMBL11790912 | 0.78 | DRD2 (0.79) | CCR1DRD2SIGMAR1DRD3LMNA | |
| SCHEMBL11801584 | 0.78 | DRD2 (0.79) | CCR1DRD2SIGMAR1DRD3LMNA | |
| SCHEMBL28849066 | 0.77 | DRD2 (1.00) | DRD2SIGMAR1DRD3OPRM1 | |
| SCHEMBL9108276 | 0.77 | CCR1 (1.00) | CCR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1996002250-A1 | HALOPERIDOL ANALOGS AND THE USE THEREOF | ACEA PHARMACEUTICALS INC. (US) | 1996-02-01 | — | — | WO | disclosed |