Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDGFRB | P09619 | 1/20 | 0.39 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.39 |
| ▸ | KIT | P10721 | 3/20 | 0.37 |
| ▸ | FLT3 | P36888 | 2/20 | 0.36 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.36 |
| ▸ | NPC1 | O15118 | 4/20 | 0.36 |
| ▸ | RAB9A | P51151 | 4/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.36 |
| ▸ | GLA | P06280 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.36 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.36 |
| ▸ | RELA | Q04206 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6620248 | 0.91 | PDGFRB (0.46) | PDGFRBPDGFRAKITFLT3GRIN2B | |
| SCHEMBL6617184 | 0.91 | PDGFRB (0.46) | PDGFRBPDGFRAKITFLT3GRIN2B | |
| SCHEMBL9053687 | 0.79 | PDGFRB (0.43) | PDGFRBPDGFRAKITFLT3ALDH1A1 | |
| SCHEMBL6617252 | 0.77 | PDGFRB (0.50) | PDGFRBPDGFRAKITFLT3ALDH1A1 | |
| SCHEMBL6620040 | 0.77 | PDGFRB (0.50) | PDGFRBPDGFRAKITFLT3GRIN2B | |
| SCHEMBL9059921 | 0.76 | GRIN2B (0.38) | PDGFRBPDGFRAKITFLT3GRIN2B | |
| SCHEMBL6620856 | 0.76 | KIT (0.44) | PDGFRBPDGFRAKITFLT3GRIN2B | |
| SCHEMBL6616763 | 0.76 | GRIN2B (0.47) | PDGFRBPDGFRAKITFLT3GRIN2B | |
| SCHEMBL9060048 | 0.75 | GRIN2B (0.41) | PDGFRBPDGFRAKITFLT3GRIN2B | |
| SCHEMBL6617430 | 0.75 | MET (0.44) | PDGFRBPDGFRAKITFLT3GRIN2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1996007658-A1 | PYRAZOLO[3,4-g]QUINOXALINE COMPOUNDS WHICH INHIBIT PDGF RECEPTOR PROTEIN TYROSINE KINASE | RHONE-POULENC RORER PHARMACEUTICALS INC. (US) | 1996-03-14 | — | — | WO | disclosed |