Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | UBE2N | P61088 | 1/20 | 0.40 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | LAP3 | P28838 | 2/20 | 0.36 |
| ▸ | ANPEP | P15144 | 1/20 | 0.36 |
| ▸ | RNPEP | Q9H4A4 | 1/20 | 0.36 |
| ▸ | DNPEP | Q9ULA0 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.36 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.36 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.36 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.35 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.35 |
| ▸ | ALPI | P09923 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.35 |
| ▸ | XIAP | P98170 | 1/20 | 0.35 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.35 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.35 |
| ▸ | MMP9 | P14780 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9058944 | 0.88 | OPRM1 (0.39) | UBE2NCHRM1HPGDLAP3ANPEP | |
| SCHEMBL6354283 | 0.74 | UBE2N (0.36) | UBE2NCHRM1HPGDOPRD1 | |
| Hydrochloric Acid SCHEMBL9052256 | 0.71 | HPGD (0.41) | UBE2NHPGDLAP3ANPEPRNPEP | |
| Hydrochloric Acid SCHEMBL9052110 | 0.68 | ABCB1 (0.40) | UBE2NCHRM1HPGDLAP3EPHX1 | |
| SCHEMBL6249330 | 0.65 | CCR1 (0.50) | UBE2NCHRM1HPGDEPHX1ALPI | |
| SCHEMBL6161100 | 0.65 | ALPI (0.51) | UBE2NCHRM1HPGDHTTALPI | |
| SCHEMBL3055250 | 0.65 | ABCB1 (0.44) | HPGDEPHX1ABCB1ALPIPKM | |
| SCHEMBL3049880 | 0.65 | ABCB1 (0.44) | HPGDEPHX1ABCB1ALPIPKM | |
| SCHEMBL3049974 | 0.65 | ABCB1 (0.44) | HPGDEPHX1ABCB1ALPIPKM | |
| SCHEMBL5766398 | 0.65 | UBE2N (0.51) | UBE2NCHRM1HPGDALPIPKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1996039385-A1 | SUBSTITUTED N-(INDOLE-2-CARBONYL-) AMIDES AND DERIVATIVES AS GLYCOGEN PHOSPHORYLASE INHIBITORS | PFIZER INC. (US) | 1996-12-12 | — | — | WO | disclosed |