Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER1 | P34995 | 8/20 | 0.57 |
| ▸ | C3AR1 | Q16581 | 4/20 | 0.55 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | THPO | P40225 | 1/20 | 0.48 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.48 |
| ▸ | PTGER2 | P43116 | 4/20 | 0.47 |
| ▸ | GRM5 | P41594 | 1/20 | 0.43 |
| ▸ | FNTA | P49354 | 1/20 | 0.42 |
| ▸ | FNTB | P49356 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9275201 | 0.97 | PTGER1 (0.55) | PTGER1C3AR1MEN1KMT2AALDH1A1 | |
| SCHEMBL9275455 | 0.91 | FNTA (0.52) | PTGER1MEN1KMT2AALDH1A1CYP1A2 | |
| SCHEMBL9275910 | 0.90 | PTGER1 (0.69) | PTGER1C3AR1MEN1KMT2AALDH1A1 | |
| SCHEMBL9053229 | 0.84 | PKM (0.53) | PTGER1MEN1KMT2AALDH1A1CYP1A2 | |
| SCHEMBL9275934 | 0.83 | PTGER1 (0.61) | PTGER1MEN1KMT2AALDH1A1CYP1A2 | |
| SCHEMBL9269919 | 0.81 | PTGER1 (0.51) | PTGER1MEN1KMT2AALDH1A1CYP1A2 | |
| SCHEMBL9269394 | 0.81 | PTGER1 (0.61) | PTGER1MEN1KMT2AALDH1A1CYP1A2 | |
| SCHEMBL9277986 | 0.81 | PTGER1 (0.59) | PTGER1MEN1KMT2AALDH1A1CYP1A2 | |
| SCHEMBL9275435 | 0.81 | PTGER1 (0.66) | PTGER1MEN1KMT2AALDH1A1CYP1A2 | |
| SCHEMBL9273093 | 0.81 | AVPR1A (0.57) | PTGER1MEN1KMT2AALDH1A1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0703908-A1 | ANALGESIC DIBENZOXAZEPINES AND DIBENZOTHIAZEPINES | G.D. SEARLE & CO. (US) | 1996-04-03 | — | — | EP | claimed |
| WO-1994029286-A1 | ANALGESIC DIBENZOXAZEPINES AND DIBENZOTHIAZEPINES | G.D. SEARLE & CO. (US) | 1994-12-22 | — | — | WO | claimed |
| US-5461047-A | Analgesics and treats prostaglandin-E2 mediated diseases in animals | G. D. SEARLE & CO. (US) | 1995-10-24 | — | — | US | disclosed |