Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | CYP1A1 | P04798 | 2/20 | 0.32 |
| ▸ | MAOA | P21397 | 1/20 | 0.30 |
| ▸ | MAOB | P27338 | 1/20 | 0.30 |
| ▸ | NUAK1 | O60285 | 1/20 | 0.30 |
| ▸ | IGF1R | P08069 | 1/20 | 0.30 |
| ▸ | MET | P08581 | 1/20 | 0.30 |
| ▸ | PIM1 | P11309 | 1/20 | 0.30 |
| ▸ | SRC | P12931 | 1/20 | 0.30 |
| ▸ | AXL | P30530 | 1/20 | 0.30 |
| ▸ | AKT1 | P31749 | 1/20 | 0.30 |
| ▸ | KDR | P35968 | 1/20 | 0.30 |
| ▸ | NEK2 | P51955 | 1/20 | 0.30 |
| ▸ | PLK1 | P53350 | 1/20 | 0.30 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.30 |
| ▸ | PKN1 | Q16512 | 1/20 | 0.30 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.30 |
| ▸ | NEK6 | Q9HC98 | 1/20 | 0.30 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9050792 | 0.88 | KDM4E (0.35) | KDM4ELMNANUAK1IGF1RMET | |
| SCHEMBL9053944 | 0.70 | KDM4E (0.39) | KDM4ELMNACYP1A1NUAK1IGF1R | |
| SCHEMBL12586768 | 0.67 | KDM4E (0.39) | KDM4ELMNANUAK1IGF1RMET | |
| SCHEMBL12586920 | 0.67 | KDM4E (0.40) | KDM4ELMNANUAK1IGF1RMET | |
| SCHEMBL12586660 | 0.67 | KDM4E (0.42) | KDM4ELMNANUAK1IGF1RMET | |
| SCHEMBL8575822 | 0.66 | KDM4E (0.42) | KDM4ELMNACYP1A1NUAK1IGF1R | |
| SCHEMBL6204130 | 0.65 | KDM4E (0.57) | KDM4ELMNANUAK1IGF1RMET | |
| SCHEMBL4858597 | 0.65 | S1PR4 (0.43) | KDM4ELMNA | |
| SCHEMBL31496882 | 0.65 | MAOA (0.39) | KDM4ELMNAMAOAMAOB | |
| SCHEMBL12586621 | 0.64 | EGFR (0.44) | KDM4ELMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1996003124-A1 | DYNEMICIN ANALOGS | CALIFORNIA INSTITUTE OF TECHNOLOGY (US) | 1996-02-08 | — | — | WO | disclosed |