Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SETD7 | Q8WTS6 | 3/20 | 0.59 |
| ▸ | HTR1A | P08908 | 6/20 | 0.47 |
| ▸ | DRD2 | P14416 | 5/20 | 0.47 |
| ▸ | DRD3 | P35462 | 4/20 | 0.47 |
| ▸ | HTR2A | P28223 | 3/20 | 0.47 |
| ▸ | HTR6 | P50406 | 3/20 | 0.47 |
| ▸ | HTR7 | P34969 | 3/20 | 0.47 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.47 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.47 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.47 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.47 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.47 |
| ▸ | DRD1 | P21728 | 2/20 | 0.47 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.47 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.47 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.47 |
| ▸ | HRH1 | P35367 | 2/20 | 0.47 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.47 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.47 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9053127 | 0.99 | SETD7 (0.61) | SETD7HTR1ADRD2DRD3HTR2A | |
| SCHEMBL9053843 | 0.97 | SETD7 (0.57) | SETD7HTR1ADRD2DRD3HTR2A | |
| SCHEMBL9053971 | 0.85 | SETD7 (0.56) | SETD7HTR1ADRD2DRD3HTR2A | |
| SCHEMBL9054448 | 0.82 | SETD7 (0.49) | SETD7HTR1ADRD2DRD3HTR7 | |
| SCHEMBL6256621 | 0.80 | SETD7 (0.59) | SETD7HTR1ADRD2DRD3HTR2A | |
| SCHEMBL29367087 | 0.80 | SETD7 (0.59) | SETD7HTR1ADRD2DRD3HTR2A | |
| SCHEMBL9036131 | 0.78 | SETD7 (0.70) | SETD7HTR1ADRD2DRD3HTR2A | |
| Hydrochloric Acid SCHEMBL7212357 | 0.77 | SETD7 (0.68) | SETD7HTR1ADRD2DRD3HTR2A | |
| SCHEMBL7218739 | 0.77 | SETD7 (0.75) | SETD7HTR1ADRD2DRD3HTR2A | |
| Hydrochloric Acid SCHEMBL7218685 | 0.76 | SETD7 (0.70) | SETD7HTR1ADRD2DRD3HTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0706522-A1 | TETRAZOLE DERIVATIVES HAVING ANTIHISTAMINIC AND ANTIALLERGIC ACTIVITY | SUMITOMO METAL INDUSTRIES, LTD. (JP) | 1996-04-17 | — | — | EP | disclosed |
| WO-1995001350-A1 | TETRAZOLE DERIVATIVES HAVING ANTIHISTAMINIC AND ANTIALLERGIC ACTIVITY | SUMITOMO METAL INDUSTRIES, LTD. (JP) | 1995-01-12 | — | — | WO | disclosed |