Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SETD7 | Q8WTS6 | 5/20 | 0.49 |
| ▸ | DRD2 | P14416 | 3/20 | 0.36 |
| ▸ | DRD3 | P35462 | 3/20 | 0.36 |
| ▸ | HTR1A | P08908 | 2/20 | 0.36 |
| ▸ | HTR7 | P34969 | 1/20 | 0.36 |
| ▸ | HRH1 | P35367 | 1/20 | 0.36 |
| ▸ | PARP1 | P09874 | 2/20 | 0.35 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.34 |
| ▸ | DRD4 | P21917 | 1/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.32 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.32 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9053843 | 0.85 | SETD7 (0.57) | SETD7DRD2DRD3HTR1AHTR7 | |
| SCHEMBL9053582 | 0.82 | SETD7 (0.59) | SETD7DRD2DRD3HTR1AHTR7 | |
| SCHEMBL9053127 | 0.81 | SETD7 (0.61) | SETD7DRD2DRD3HTR1AHTR7 | |
| SCHEMBL9053460 | 0.72 | P2RX7 (0.47) | SETD7DRD2DRD3HTR1AHTR7 | |
| SCHEMBL11600139 | 0.71 | SETD7 (0.58) | SETD7DRD2DRD3HTR1AHTR7 | |
| SCHEMBL9053971 | 0.71 | SETD7 (0.56) | SETD7DRD2DRD3HTR1AHTR7 | |
| SCHEMBL10194165 | 0.70 | DRD3 (0.51) | DRD2DRD3HTR1AHTR7HRH1 | |
| SCHEMBL9054797 | 0.70 | HTR7 (0.47) | DRD2DRD3HTR7SIGMAR1DRD4 | |
| SCHEMBL9061799 | 0.70 | — | — | |
| Hydrochloric Acid SCHEMBL11600821 | 0.70 | SETD7 (0.57) | SETD7DRD2DRD3HTR1AHTR7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0706522-A1 | TETRAZOLE DERIVATIVES HAVING ANTIHISTAMINIC AND ANTIALLERGIC ACTIVITY | SUMITOMO METAL INDUSTRIES, LTD. (JP) | 1996-04-17 | — | — | EP | disclosed |
| WO-1995001350-A1 | TETRAZOLE DERIVATIVES HAVING ANTIHISTAMINIC AND ANTIALLERGIC ACTIVITY | SUMITOMO METAL INDUSTRIES, LTD. (JP) | 1995-01-12 | — | — | WO | disclosed |