SCHEMBL9053836

SCHEMBL9053836

O=C(CI)c1ccc(O)c(O)c1

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA12 O43570 3/20 0.56
CA1 P00915 3/20 0.56
CA2 P00918 3/20 0.56
CA7 P43166 3/20 0.56
CA9 Q16790 3/20 0.56
CA14 Q9ULX7 3/20 0.56
KDM4E B2RXH2 2/20 0.56
GAA P10253 2/20 0.56
L3MBTL1 Q9Y468 2/20 0.56
POLB P06746 2/20 0.56
MAPT P10636 1/20 0.56
CA4 P22748 1/20 0.56
CA6 P23280 1/20 0.56
PTGS2 P35354 1/20 0.56
PLAA Q9Y263 4/20 0.53
GSK3B P49841 1/20 0.52
ALPG P10696 8/20 0.51
ALPL P05186 4/20 0.50
HDAC6 Q9UBN7 1/20 0.50
DBH P09172 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30309722 1.00 CA12 (0.56) CA12CA1CA2CA7CA9
Acetone SCHEMBL28989821 0.94 CA12 (0.50) CA12CA1CA2CA7CA9
SCHEMBL11455991 0.80 ALDH1A1 (0.52) CA12CA1CA2CA7CA9
SCHEMBL11447833 0.80 CA1 (0.52) CA12CA1CA2CA7CA9
SCHEMBL31509307 0.80 CA12 (0.58) CA12CA1CA2CA7CA9
SCHEMBL105705 0.80 CA12 (0.58) CA12CA1CA2CA7CA9
SCHEMBL11455846 0.79 GSK3B (0.44) CA12CA1CA2CA7CA9
SCHEMBL8343669 0.78 PTPN1 (0.59) CA12CA1CA2CA7CA9
SCHEMBL16010437 0.78 CA12 (0.56) CA12CA1CA2CA7CA9
SCHEMBL2991009 0.78 CA12 (0.58) CA12CA1CA2CA7CA9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023102567-A2 GRAFTABLE BIOCIDAL LINKERS AND POLYMERS AND USES THEREOF DEBOGY MOLECULAR, INC. (US) 2023-06-08 WO disclosed
WO-2023102567-A2 GRAFTABLE BIOCIDAL LINKERS AND POLYMERS AND USES THEREOF DEBOGY MOLECULAR, INC. (US) 2023-06-08 WO disclosed
CN-115988962-A Graftable biocidal linkers and polymers and uses thereof 德保吉分子公司 2023-04-18 CN disclosed
EP-0435333-B1 Cephalosporin derivatives, the process for preparing the same, and antimicrobial composition containing the derivatives OTSUKA PHARMA CO LTD (JP) 1996-06-05 EP disclosed
US-5262411-A Isocephem derivatives, and antimicrobial composition containing the derivatives OTSUKA PHARMACEUTICAL CO., LTD. (JP) 1993-11-16 US disclosed
EP-0435333-A2 Cephalosporin derivatives, the process for preparing the same, and antimicrobial composition containing the derivatives OTSUKA PHARMACEUTICAL CO., LTD. (JP) 1991-07-03 EP disclosed