⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12792 | 0.97 | — | — | |
| SCHEMBL14127455 | 0.97 | — | — | |
| SCHEMBL29432874 | 0.97 | — | — | |
| Ammonia Solution, Strong SCHEMBL10934390 | 0.94 | TSHR (0.53) | — | |
| Fluoride SCHEMBL27287101 | 0.94 | — | — | |
| SCHEMBL28873613 | 0.94 | — | — | |
| Hydrochloric Acid SCHEMBL9527099 | 0.94 | — | — | |
| 1,2-Dichlorobenzene SCHEMBL521767 | 0.94 | TSHR (0.62) | — | |
| SCHEMBL31131455 | 0.94 | — | — | |
| Bromide SCHEMBL27311011 | 0.94 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 96 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114181142-A | Synthetic method of 6- (4-methylpiperazine-1-yl) -4-o-tolylnicotinamide | 浙江工业大学 | 2022-03-15 | — | — | CN | claimed |
| US-4902833-A | Bisphosphine dioxides | UNION CARBIDE CHEMICALS AND PLASTICS COMPANY INC. (US) | 1990-02-20 | — | — | US | claimed |
| US-20250282729-A1 | CHEMICAL COMPOUND MANUFACTURE, NEW SALT FORM, AND THERAPEUTIC USES THEREOF | EUSTRALIS PHARMACEUTICALS LIMITED (TRADING AS PRESSURA NEURO) (AU) | 2025-09-11 | — | — | US | disclosed |
| US-12351557-B2 | Chemical compound manufacture, new salt form, and therapeutic uses thereof | EUSTRALIS PHARMACEUTICALS LIMITED (AU) | 2025-07-08 | — | — | US | disclosed |
| US-12281076-B2 | Process for synthesis of picolinamides | CORTEVA AGRISCIENCE LLC (US) | 2025-04-22 | — | — | US | disclosed |
| US-20220411375-A1 | PROCESS FOR SYNTHESIS OF PICOLINAMIDES | CORTEVA AGRISCIENCE LLC (US) | 2022-12-29 | — | — | US | disclosed |
| EP-4044811-A1 | PROCESS FOR SYNTHESIS OF PICOLINAMIDES | Corteva Agriscience LLC (US) | 2022-08-24 | — | — | EP | disclosed |
| CN-114554848-A | Process for the synthesis of picolinamides | 科迪华农业科技有限责任公司 | 2022-05-27 | — | — | CN | disclosed |
| CN-114409602-A | Method for synthesizing alpha-keto acid by using oxalyl chloride and Grignard reagent as raw materials | 武汉大学 | 2022-04-29 | — | — | CN | disclosed |
| CN-109748921-B | N-tert-butyloxycarbonyl protected heterocyclic compound, preparation method thereof and method for preparing C-nucleoside analogue by using N-tert-butyloxycarbonyl protected heterocyclic compound | 中国科学院上海药物研究所 | 2022-03-22 | — | — | CN | disclosed |
| CN-114181142-A | Synthetic method of 6- (4-methylpiperazine-1-yl) -4-o-tolylnicotinamide | 浙江工业大学 | 2022-03-15 | — | — | CN | disclosed |
| EP-0895992-A2 | Copper complexes of optically active bisoxazolines as enantioselective catalysts in cyclopropanation reactions | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1999-02-10 | — | — | EP | disclosed |
| EP-0728128-B1 | SUBSTITUTED PHENYL COMPOUNDS | RHONE POULENC RORER LTD (GB) | 1998-09-16 | — | — | EP | disclosed |
| EP-0811612-A1 | Process for preparing dithiocarbonimide derivatives | SUMITOMO CHEMICAL COMPANY LIMITED (JP) | 1997-12-10 | — | — | EP | disclosed |
| EP-0728128-A1 | SUBSTITUTED PHENYL COMPOUNDS | RHONE-POULENC RORER LIMITED (GB) | 1996-08-28 | — | — | EP | disclosed |
| WO-1995013262-A1 | SUBSTITUTED PHENYL COMPOUNDS | RHONE-POULENC RORER LIMITED (GB) | 1995-05-18 | — | — | WO | disclosed |
| US-4902833-A | Bisphosphine dioxides | UNION CARBIDE CHEMICALS AND PLASTICS COMPANY INC. (US) | 1990-02-20 | — | — | US | disclosed |
| US-4683344-A | REACTION OF HYDROXY OR AMIDE COMPOUND WITH GRIGNARD, REAGENT SOLID STATE | PPG INDUSTRIES, INC. (US) | 1987-07-28 | — | — | US | disclosed |
| US-4599398-A | GRIGNARD CATALYST, DUAL INITIATOR | PPG INDUSTRIES, INC. (US) | 1986-07-08 | — | — | US | disclosed |
| US-4501821-A | HETEROCYCLIC IMIDES OR ACYLUREAS AND POLYMERS HAVING THESE END GROUPS; MOLDING POLYCAPROLACTAM | PPG INDUSTRIES, INC. (US) | 1985-02-26 | — | — | US | disclosed |