Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.62 |
| ▸ | LMNA | P02545 | 1/20 | 0.62 |
| ▸ | ACHE | P22303 | 2/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | CA7 | P43166 | 1/20 | 0.41 |
| ▸ | CA9 | Q16790 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.40 |
| ▸ | PLA2G7 | Q13093 | 1/20 | 0.40 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | CYP2A6 | P11509 | 6/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 5/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12792 | 0.97 | — | — | |
| SCHEMBL14127455 | 0.97 | — | — | |
| SCHEMBL29432874 | 0.97 | — | — | |
| SCHEMBL28873613 | 0.94 | — | — | |
| Ammonia Solution, Strong SCHEMBL10934390 | 0.94 | TSHR (0.53) | TSHRLMNAACHEALDH1A1CA1 | |
| Hydrochloric Acid SCHEMBL9552818 | 0.94 | TSHR (0.53) | TSHRLMNAACHEALDH1A1CA1 | |
| Hydrochloric Acid SCHEMBL9527099 | 0.94 | — | — | |
| SCHEMBL905386 | 0.94 | — | — | |
| SCHEMBL31131455 | 0.94 | — | — | |
| SCHEMBL4934521 | 0.91 | TSHR (0.50) | TSHRLMNAACHEALDH1A1CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120029202-A1 | Process for the Preparation of 5-Substituted 3-Aryl-3-(trifluoromethyl)-3,4-dihydro-2H-pyrroles | BAYER CROPSCIENCE AG (DE) | 2012-02-02 | — | — | US | disclosed |
| WO-2011141414-A1 | PROCESS FOR THE PREPARATION OF 5-SUBSTITUTED 3-ARYL-3-(TRIFLUOROMETHYL)-3,4-DIHYDRO-2H-PYRROLES | BAYER CROPSCIENCE AG (DE) | 2011-11-17 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120029202-A1 | Process for the Preparation of 5-Substituted 3-Aryl-3-(trifluoromethyl)-3,4-dihydro-2H-pyrroles | CYP4F3, PAH, IDH3B | TSHR 2370/4885LMNA 2215/4885ACHE 2588/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.