Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | RECQL | P46063 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.41 |
| ▸ | POLB | P06746 | 3/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9494274 | 0.74 | LMNA (0.52) | LMNAMAPK1TSHRMAPTRECQL | |
| SCHEMBL9494278 | 0.74 | LMNA (0.52) | LMNAMAPK1TSHRMAPTRECQL | |
| SCHEMBL29780034 | 0.73 | LMNA (0.49) | LMNAMAPK1TSHRMAPTRECQL | |
| SCHEMBL9053874 | 0.73 | LMNA (0.49) | LMNAMAPK1TSHRMAPTRECQL | |
| SCHEMBL12186945 | 0.73 | LMNA (0.49) | LMNAMAPK1TSHRMAPTRECQL | |
| SCHEMBL11819609 | 0.73 | LMNA (0.61) | LMNAMAPK1TSHRMAPTRECQL | |
| SCHEMBL11819614 | 0.73 | LMNA (0.61) | LMNAMAPK1TSHRMAPTRECQL | |
| Phosphoric Acid SCHEMBL11090384 | 0.71 | LMNA (0.49) | LMNAMAPK1TSHRMAPTRECQL | |
| SCHEMBL9147402 | 0.70 | LMNA (0.57) | LMNAMAPK1TSHRMAPTRECQL | |
| SCHEMBL9312423 | 0.70 | LMNA (0.57) | LMNAMAPK1TSHRMAPTRECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0508955-B1 | Use of 2-iminothiazolidin-4-one derivatives as new medicaments | CIBA GEIGY AG (CH) | 1996-06-19 | — | — | EP | claimed |