Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHODH | Q02127 | 18/20 | 0.59 |
| ▸ | DHFR | P00374 | 1/20 | 0.59 |
| ▸ | ALKBH5 | Q6P6C2 | 1/20 | 0.59 |
| ▸ | PDE10A | Q9Y233 | 2/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9053927 | 0.92 | DHODH (0.55) | DHODHDHFRALKBH5PDE10A | |
| SCHEMBL8686065 | 0.90 | DHODH (0.74) | DHODHDHFRALKBH5PDE10A | |
| SCHEMBL9052974 | 0.89 | DHODH (0.68) | DHODHDHFRALKBH5PDE10A | |
| SCHEMBL9052731 | 0.85 | DHODH (0.60) | DHODHDHFRALKBH5PDE10A | |
| SCHEMBL8686055 | 0.84 | DHODH (0.62) | DHODHDHFRALKBH5PDE10A | |
| SCHEMBL8686969 | 0.78 | DHODH (0.52) | DHODHDHFRALKBH5PDE10A | |
| SCHEMBL17593892 | 0.77 | DHODH (0.68) | DHODHDHFRALKBH5PDE10A | |
| Brequinar SCHEMBL23832490 | 0.74 | DHODH (1.00) | DHODHDHFRALKBH5PDE10A | |
| Brequinar SCHEMBL49400 | 0.74 | DHODH (1.00) | DHODHDHFRALKBH5PDE10A | |
| Brequinar SCHEMBL29688590 | 0.74 | DHODH (1.00) | DHODHDHFRALKBH5PDE10A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0702726-A1 | IMMUNOASSAY REAGENTS AND METHODS FOR DETECTING BREQUINAR AND ANALOGS | THE DU PONT MERCK PHARMACEUTICAL COMPANY (US) | 1996-03-27 | — | — | EP | disclosed |