Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHODH | Q02127 | 19/20 | 0.52 |
| ▸ | DHFR | P00374 | 1/20 | 0.52 |
| ▸ | ALKBH5 | Q6P6C2 | 1/20 | 0.52 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8686055 | 0.85 | DHODH (0.62) | DHODHDHFRALKBH5PDE10A | |
| SCHEMBL9052731 | 0.84 | DHODH (0.60) | DHODHDHFRALKBH5PDE10A | |
| SCHEMBL8686065 | 0.83 | DHODH (0.74) | DHODHDHFRALKBH5PDE10A | |
| SCHEMBL9052974 | 0.79 | DHODH (0.68) | DHODHDHFRALKBH5PDE10A | |
| SCHEMBL9053932 | 0.78 | DHODH (0.59) | DHODHDHFRALKBH5PDE10A | |
| SCHEMBL9053927 | 0.78 | DHODH (0.55) | DHODHDHFRALKBH5PDE10A | |
| SCHEMBL8691406 | 0.71 | DHODH (0.82) | DHODHDHFRALKBH5PDE10A | |
| SCHEMBL6309767 | 0.70 | DHODH (0.70) | DHODHDHFRALKBH5PDE10A | |
| SCHEMBL9488317 | 0.70 | DHODH (0.81) | DHODHDHFRALKBH5PDE10A | |
| SCHEMBL17593848 | 0.69 | PTGFR (0.68) | DHODHDHFRALKBH5PDE10A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5707844-A | QUINOLINECARBOXYLIC ACID SALTS AS HAPTAN SPECIFIC ANTIBODIES | THE DUPONT MERCK PHARMACEUTICAL COMPANY (US) | 1998-01-13 | — | — | US | disclosed |
| US-5393891-A | Useful as standards in testing for presence of quinoline carboxylic acids | THE DU PONT MERCK PHARMACEUTICAL COMPANY (US) | 1995-02-28 | — | — | US | disclosed |
| WO-1994029478-A1 | IMMUNOASSAY REAGENTS AND METHODS FOR DETECTING BREQUINAR AND ANALOGS | THE DU PONT MERCK PHARMACEUTICAL COMPANY (US) | 1994-12-22 | — | — | WO | disclosed |