Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARA | P10276 | 1/20 | 0.36 |
| ▸ | RARB | P10826 | 1/20 | 0.36 |
| ▸ | RARG | P13631 | 1/20 | 0.36 |
| ▸ | HSPA9 | P38646 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.34 |
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | APAF1 | O14727 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7194958 | 0.93 | RARA (0.36) | RARARARBRARGHSPA9CYP3A4 | |
| SCHEMBL9055225 | 0.77 | RARA (0.38) | RARARARBRARGHSPA9ALDH1A1 | |
| SCHEMBL7195918 | 0.74 | KDM4E (0.50) | RARARARBRARGHSPA9TDP1 | |
| SCHEMBL9053795 | 0.74 | MEN1 (0.46) | RARARARBRARGHSPA9TDP1 | |
| SCHEMBL9054067 | 0.73 | RARA (0.38) | RARARARBRARGHSPA9ALDH1A1 | |
| SCHEMBL9054107 | 0.72 | RARA (0.36) | RARARARBRARGCYP3A4TSHR | |
| Hydrochloric Acid SCHEMBL21750654 | 0.72 | KDM4E (0.49) | RARARARBRARGHSPA9TDP1 | |
| SCHEMBL8561089 | 0.72 | RARA (0.34) | RARARARBRARGHSPA9 | |
| SCHEMBL7217368 | 0.71 | RARA (0.38) | RARARARBRARGHSPA9CYP3A4 | |
| SCHEMBL5737717 | 0.70 | RARA (0.46) | RARARARBRARGHSPA9TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5498755-A | IMINE COMPOUNDS FOR SKIN DISORDERS AND ANTIINFLAMMATORY AGENTS | ALLERGAN, INC. | 1996-03-12 | — | — | US | disclosed |
| WO-1996006070-A1 | DISUBSTITUTED ARYL AND HETEROARYL IMINES HAVING RETINOID-LIKE BIOLOGICAL ACTIVITY | ALLERGAN (US) | 1996-02-29 | — | — | WO | disclosed |