SCHEMBL9054

SCHEMBL9054

[O]C(F)(F)CF

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2834936 0.73
SCHEMBL1186983 0.73
SCHEMBL477967 0.73
SCHEMBL6594970 0.73
SCHEMBL477719 0.73
SCHEMBL66564 0.70
SCHEMBL7857336 0.70
SCHEMBL4951773 0.70
SCHEMBL2305635 0.70
SCHEMBL4463822 0.70

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 11238 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115232117-B Substituted isoxazole pyrimidine amine compound, preparation method and application thereof 沈阳中化农药化工研发有限公司 2024-07-16 CN claimed
CN-118234706-A Substituted sulfite compound and preparation method and application thereof 青岛康乔药业集团有限公司 2024-06-21 CN claimed
WO-2024126388-A1 PESTICIDALLY ACTIVE HETEROCYCLIC DERIVATIVES WITH SULFUR CONTAINING SUBSTITUENTS SYNGENTA CROP PROTECTION AG (CH) 2024-06-20 WO claimed
WO-2024125668-A1 HETEROCYCLIC SUBSTITUTED PENTA-SIX-MEMBERED HETEROARYL DERIVATIVE, PHARMACEUTICAL COMPOSITION THEREOF, AND APPLICATION AND PREPARATION METHOD THEREFOR 上海海雁医药科技有限公司 2024-06-20 WO claimed
EP-4384500-A1 PHENOXY-ACETYL-THIOUREIDO-BENZENESULFONAMIDE DERIVATIVES, AND THEIR USES Centre National de la Recherche Scientifique (FR) 2024-06-19 EP claimed
CN-118215661-A Compounds as BCL-2 inhibitors 重庆复创医药研究有限公司 2024-06-18 CN claimed
CN-117936947-B Solid electrolyte of lithium battery and preparation method thereof 广州鑫虹兴电子有限公司 2024-05-31 CN claimed
CN-118084887-A Azole alcohol compound, preparation method and antifungal drug 上海市第十人民医院 2024-05-28 CN claimed
WO-2024104344-A1 QUINOLINECARBOXYLIC ACID DERIVATIVE AND USE THEREOF 沈阳中化农药化工研发有限公司 2024-05-23 WO claimed
CN-118055932-A KRAS inhibitor and preparation and pharmaceutical application thereof 上海和誉生物医药科技有限公司 2024-05-17 CN claimed
EP-0133259-A2 Aminoalkyl-substituted benzene derivatives, process for production thereof, and pharmaceutical composition thereof KOWA COMPANY, LTD. (JP) 1985-02-20 EP claimed
EP-0115828-A1 Substituted oxime ether BAYER AG (DE) 1984-08-15 EP claimed
US-4439438-A ANTIDEPRESSANTS, INOTROPIC AGENTS CAVAZZA CLAUDIO (IT) 1984-03-27 US claimed
US-4412053-A THERMAL DECOMPOSITION OF N-SILYLPHOSPHINIMINES NEILSON ROBERT H 1983-10-25 US claimed
US-4329460-A ANTICANCER AGENTS, ANTIVIRAL AGENTS TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 1982-05-11 US claimed
US-4242499-A Colored polymers comprising poly(organophosphazenes) with chromophores as substituent groups THE FIRESTONE TIRE & RUBBER COMPANY (US) 1980-12-30 US claimed
US-4221904-A Polyphosphazene copolymers containing substituents derived from pyruvate esters THE FIRESTONE TIRE & RUBBER COMPANY (US) 1980-09-09 US claimed
EP-0006969-A1 A polyphosphazene composition stabilized against thermal aging and use therof THE FIRESTONE TIRE & RUBBER COMPANY (US) 1980-01-23 EP claimed
US-4139523-A HEAT AGING RESISTANCE THE FIRESTONE TIRE & RUBBER COMPANY (US) 1979-02-13 US claimed
US-4051103-A Stabilization of polyfluorophosphazenes with zinc hippurate THE FIRESTONE TIRE & RUBBER COMPANY (US) 1977-09-27 US claimed