SCHEMBL66564

SCHEMBL66564

[O]C(F)(F)C(F)(F)CF

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4426696 0.79
SCHEMBL9482464 0.74
SCHEMBL727839 0.74
SCHEMBL6598205 0.72
SCHEMBL9054 0.70
SCHEMBL8524771 0.69
SCHEMBL15402187 0.67
SCHEMBL32838 0.67
SCHEMBL867114 0.67
SCHEMBL8582545 0.67

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 556 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117327000-A Biphenyl tetrahydropyrrole compound and preparation method and application thereof 海南因瑞生物医药科技有限公司 2024-01-02 CN claimed
CN-115232129-B PARP1 selective inhibitor and preparation method and application thereof 上海闻耐医药科技有限公司 2023-12-01 CN claimed
US-20230192620-A1 ANILINE COMPOUND USED AS RORy REGULATOR SHANGHAI LITEDD CO., LTD. (CN) 2023-06-22 US claimed
EP-4151626-A1 ANILINE COMPOUND USED AS RORy REGULATOR Shanghai Litedd Co., Ltd. (CN) 2023-03-22 EP claimed
CN-112080130-B Thermoplastic polyurethane elastomer/fluororubber blending material and preparation method thereof 万华化学集团股份有限公司 2022-11-04 CN claimed
CN-112080129-B Radiation-vulcanized thermoplastic polyurethane elastomer/fluororubber blending material and preparation method thereof 万华化学集团股份有限公司 2022-11-04 CN claimed
CN-115232129-A PARP1 selective inhibitor and preparation method and application thereof 上海闻耐医药科技有限公司 2022-10-25 CN claimed
CN-113773251-A Anilines useful as ROR gamma modulators 上海辉启生物医药科技有限公司 2021-12-10 CN claimed
CN-112470311-A Electrolyte with phosphite as additive or cosolvent, lithium secondary battery containing electrolyte and method for preparing phosphite 于利奇研究中心有限公司 2021-03-09 CN claimed
CN-112080129-A Radiation-vulcanized thermoplastic polyurethane elastomer/fluororubber blending material and preparation method thereof 万华化学集团股份有限公司 2020-12-15 CN claimed
WO-2014086705-A1 NOVEL PYRIDINE DERIVATIVES F. HOFFMANN-LA ROCHE AG (CH) 2014-06-12 WO claimed
EP-2718266-A1 PYRIDIN- 2 -AMIDES USEFUL AS CB2 AGONISTS F.HOFFMANN-LA ROCHE AG (CH) 2014-04-16 EP claimed
WO-2012168350-A1 PYRIDIN- 2 -AMIDES USEFUL AS CB2 AGONISTS F. HOFFMANN-LA ROCHE AG (CH) 2012-12-13 WO claimed
US-20120316147-A1 NOVEL PYRIDINE DERIVATIVES F. HOFFMANN-LA ROCHE AG (CH) 2012-12-13 US claimed
US-8318209-B2 microspheres; inner core is polymethyl methacrylate hydrogel polymer and a contrast agent; outer polyphosphazene coating; poly[bis(2,2,2-trifluoroethoxy)phosphazene]; size of particle allows selective embolization of certain blood vessels; fluoroscopy, tomography CELONOVA BIOSCIENCES GERMANY GMBH (DE) 2012-11-27 US claimed
EP-1984369-A2 NITROIMIDAZOLE COMPOUNDS Novartis AG (CH) 2008-10-29 EP claimed
WO-2007075872-A2 NITROIMIDAZOLE COMPOUNDS NOVARTIS AG (CH) 2007-07-05 WO claimed
EP-0765871-B1 Substituted Quinoline-2-carboxamides, their preparation and their use as prolyle-4-hydroxylase Inhibitors FIBROGEN INC (US) 2004-03-31 EP claimed
EP-0765871-A1 Substituted Quinoline-2-carboxamides, their preparation and their use as prolyle-4-hydroxylase Inhibitors HOECHST AKTIENGESELLSCHAFT (DE) 1997-04-02 EP claimed
EP-0400625-A2 Laminated films IDEMITSU PETROCHEMICAL CO. LTD. (JP) 1990-12-05 EP claimed